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5 / 18 resultslearn Apple stem cell
learn Osteopontin
signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss
learn PP405
mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials
learn Stemoxydine
chemical from L'Oreal that encourages hair to enter growth phase
Research
5 / 1000+ resultsresearch Microfluidic Technology for the Generation of Cell Spheroids and Their Applications
Microfluidic technology improves cell spheroid creation for better drug testing and tissue engineering.
research Advancements in Bioactive Compounds and Therapeutic Agents for Alopecia: Trends and Future Perspectives
This review discusses recent advancements in the treatment of alopecia, focusing on alopecia areata (AA) and androgenetic alopecia (AGA). It highlights the role of immune and hormonal factors in these conditions and the potential of selective inhibitors like baricitinib and ritlecitinib to restore immune balance in AA. For AGA, the review emphasizes the impact of dihydrotestosterone on follicular miniaturization and the benefits of combination therapies, including low-dose oral minoxidil and platelet-rich plasma, in promoting hair regrowth. The paper also explores the significance of intracellular signaling pathways and the potential of stem cell organoids and exosome-based therapeutics in advancing treatment from mere suppression to structural follicle reconstruction. Additionally, it underscores the importance of maintaining microbial and mitochondrial homeostasis for effective and lasting hair regeneration.
research Generation of Skin Organoids: Potential Opportunities and Challenges
Skin organoids from stem cells could better mimic real skin but face challenges.
research Studying SARS-CoV-2 Infectivity and Therapeutic Responses with Complex Organoids
Organoids can help study COVID-19 and develop treatments, but face challenges like instability and limited renewal.
research Sphingolipid Metabolism Orchestrates the Establishment of the Adult Hair Follicle Stem Cell Niche to Control Skin Homeostasis
A specific enzyme is essential for proper hair follicle stem cell development and healthy skin.
Community Join
5 / 523 resultscommunity Eirion Therapeutics Announces Potential Breakthrough Treatment for Hair Loss Based on First-in-Man Clinical Trial Results
ET-02, a new hair loss treatment, shows promising results with a 6-fold increase in hair count, potentially outperforming minoxidil by activating stem cells in hair follicles. Further trials are ongoing to confirm its efficacy and safety, with potential market release in the future.
community If we can clone a sheep why we can't cure baldness till now
Hair loss treatments like Minoxidil, finasteride, and stem cell therapies exist, but a complete cure is hindered by genetic complexity and market dynamics. Cloning hair follicles is considered a potential solution, but it's currently not feasible.
community CRISPR Is Curing People Right Now. Genetic Hair Loss is Next?
CRISPR shows promise for treating hair loss by targeting specific genes. Current treatments include Minoxidil and finasteride, but CRISPR could offer a more precise solution, though it is still expensive and in early stages.
community How ET-02 Works. Also no proof that it's better than Minoxidil. At least for now.
ET-02, a PAI-1 inhibitor, is not proven to be more effective than Minoxidil for hair loss. Other treatments like finasteride, dutasteride, PP405, and AMP-303 are also discussed, focusing on cellular senescence and oxidative stress.
community My Theory Of Androgenic Alopecia
Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.