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research Matrix Matching in Quantitative Bioanalysis by LC-MS/MS: A Dream or a Reality?
Accurate quantitative bioanalysis using LC-MS/MS is challenging due to matrix effects, but using internal standards and new methods like in-sample calibration could improve results.
research Matrix Effect in Quantitative LC/MS/MS Analyses of Biological Fluids: A Method for Determination of Finasteride in Human Plasma at Picogram Per Milliliter Concentrations
Method detects finasteride in plasma at very low concentrations.
research Separation of Finasteride and Analogues
Finasteride and analogues separated using LC-MS-MS technique.
research Revisiting Hyper- and Hypo-Androgenism by Tandem Mass Spectrometry
The document concludes that using LC-MS/MS for measuring androgens is more accurate than older methods, but it needs careful validation and standardized references to be most effective.
research Simultaneous Determination of Multi-Class Active Pharmaceutical Ingredients by UHPLC-HRMS
A new method was developed to accurately detect and measure 47 different drug ingredients in various products.
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5 / 419 resultscommunity Dutasteride Literally Saves Your Hair
Dutasteride significantly reduces scalp DHT levels and can save hair, though shedding is part of the process. Some users report success with dutasteride, while others struggle despite using it along with finasteride and oral minoxidil.
community Shedding like craaazzy but my hair is stable (I think) what the fuck honestly
Specialist_Soup_2289 is experiencing severe hair shedding despite using finasteride, dutasteride, and oral minoxidil. They hope for regrowth but are currently shedding a lot of hair.
community HUGE: Pyrilutamide seems to be stable for at least 3 weeks into KB solution. So, that means stable with water content and not degradation according to Anageninc! They will keep testing the stability further. Check the video! Many thanks to the guy AlphaMode.
The potential stability of pyrilutamide in a mixture with water, and how it could be used in combination with Minoxidil and Finasteride to treat hair loss.
community He used Dutasteride for 20 YEARS: TL;DR Slight gains and largely stable for 20 years.
John has experienced slight hair gains and stability over 20 years using Dutasteride, which is more effective than Finasteride in reducing scalp DHT and maintaining hair. Dutasteride at 0.5mg daily has a similar side effect profile to Finasteride, but at higher doses, it may increase the risk of sexual side effects.
community What’s the highest minox % you home brewed ?
A user discusses their experience with dissolving high concentrations of minoxidil in various ethanol/PG ratios and mentions difficulties with combining it with RU58841. They note that a 5% minoxidil solution remains stable, while higher concentrations tend to precipitate.