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    Glossary SRD5A2 gene

    gene converts testosterone into potent androgen DHT

    The SRD5A2 gene provides instructions for making an enzyme called steroid 5-alpha reductase type 2. This enzyme is crucial for converting testosterone into dihydrotestosterone (DHT), a more potent androgen that plays a key role in the development of male characteristics and is also implicated in conditions like male pattern baldness and certain forms of alopecia.

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    Research 10 of 490

    1. Altered methylation pattern of the SRD5A2 gene in the cerebrospinal fluid of post-finasteride patients: a pilot study Endocrine connections · 2019 · 8 citations
    2. Longer TA repeat but not V89L polymorphisms in the SRD5A2 gene may confer acne risk in the Chinese population Postępy Dermatologii i Alergologii · 2018 · 3 citations
    3. Effects on Steroid 5-Alpha Reductase Gene Expression of Thai Rice Bran Extracts and Molecular Dynamics Study on SRD5A2 Biology · 2021 · 14 citations
    4. Cloning, computational analysis and expression profiling of steroid 5 alpha-reductase 1 (SRD5A1) gene during reproductive phases and ovatide stimulation in endangered catfish, Clarias magur Scientific reports · 2023
    5. Antioxidation, Anti-Inflammation, and Regulation of SRD5A Gene Expression of Oryza sativa cv. Bue Bang 3 CMU Husk and Bran Extracts as Androgenetic Alopecia Molecular Treatment Substances Plants · 2022 · 7 citations
    6. Genetics of Polycystic Ovary Syndrome 2016 · 1 citations
    7. Differential expression of steroid 5α-reductase isozymes and association with disease severity and angiogenic genes predict their biological role in prostate cancer Endocrine Related Cancer · 2010 · 30 citations
    8. Rare and common genetic determinants of metabolic individuality and their effects on human health Nature Medicine · 2022 · 29 citations
    9. Molecular epidemiology of hypospadias: Review of genetic and environmental risk factors Birth Defects Research · 2003 · 103 citations
    10. 5α-Reductase type 2 gene variant associations with prostate cancer risk, circulating hormone levels and androgenetic alopecia International Journal of Cancer · 2006 · 57 citations
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    Community 2 of 5

    1. M44 Hairloss Trichotest and Finasteride Reddit · 7 Jun 2023
    2. Study shows further evidence that finasteride and dutasteride take 12-18 months or more to show significant results. Do NOT give up early Reddit · 25 Sept 2023
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