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An essential vasodilator with some anti-androgenic effects, has excellent safety record
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5 / 1000+ resultsresearch Evaluation of the Effects of Finasteride on Intrauterine and Early Postnatal Prostate Development in Female and Male Mongolian Gerbils (Meriones Unguiculatus)
The study investigated the effects of finasteride, a 5α-reductase inhibitor, on the prostate development of male and female Mongolian gerbils during intrauterine and early postnatal periods. Using various dosages, the research found that low-dose intrauterine exposure (100 μg/Kg/day) altered prostate development in both sexes, with increased smooth muscle thickness and stromal proliferation in females, and changes in androgen and estrogen receptor expression in males. A higher dose (500 μg/Kg/day) affected pre- and postnatal development, causing sex-specific changes in muscle thickness and epithelial proliferation. Postnatal exposure increased smooth muscle thickness and reduced developing alveoli thickness in both sexes, with more pronounced alterations in females. The findings highlighted intersex differences in response to finasteride and emphasized the need for environmental and health considerations regarding its accumulation.
research Cellular Senescence and Aging in Myotonic Dystrophy
Myotonic Dystrophy may age cells faster, and drugs that target aging could be potential treatments.
research Complications of Cataract Surgery in Wistar Rats Undergoing Treatment with Tamsulosin
Stopping tamsulosin one month before cataract surgery reduces eye surgery complications in rats.
research Androgenetic Alopecia And Hair Growth Promotion: Present And Future
Current research explores hair growth drugs, while future research aims for personalized treatments.
research Potential Factors Contributing to Androgenetic Alopecia
Male pattern baldness may be caused by factors like poor blood circulation, scalp tension, stress, and hormonal imbalances, but the exact causes are still unclear.
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5 / 175 resultscommunity hairline resurrection — 2 months before/after [5mg oral minoxidil, 1mg finasteride everyday, 2% keto shampoo every three days, weekly 0.5mm dermarolling]
This conversation was about a user named Substantial_Pen_1099 who has been using an regimen of 5mg oral minoxidil, 1mg finasteride everyday, 2% keto shampoo every three days, and weekly 0.5mm dermarolling for hair loss treatment over the course of 3 months. Others in the conversation expressed disbelief at their progress, to which Substantial_Pen_1099 provided video proof as evidence.
community Please explain this Minoxidil phenomena
The post discusses the difference in effects of Minoxidil (Min) on scalp and facial hair. The user questions why Min-induced hair growth on the scalp is temporary, while facial hair growth seems permanent, even after stopping Min. They propose theories, including different Min mechanisms on body and facial hair, the role of DHT, and the possibility of not achieving fully terminal hair. The responses include personal experiences and theories about Min's effects on hair growth.
community 5 Month Dutasteride Progress Before and After
A user experiencing significant hair loss started using Dutasteride, a drug typically used for prostate issues, and noticed a positive change in hair thickness and volume after 5 months. Other users in the conversation also shared their experiences and observations with Dutasteride, with one mentioning additional use of oral Minoxidil.
community Diffuse hair loss and scalp biopsies
Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.
community Finasteride can revive up to 7 year old dead hair
Finasteride and minoxidil can revive hair dormant for up to 7 years, with microneedling enhancing regrowth. Users report significant hair regrowth even after long periods of baldness.