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    Did you mean Small Molecule Inhibitor?
    Glossary Small Molecule Inhibitor

    blocks specific proteins or enzymes within cells

    A Small Molecule Inhibitor (SMI) is a type of drug that can enter cells easily due to its low molecular weight and can interfere with specific proteins or enzymes to block their activity. These inhibitors are often used in treatments for various diseases, including cancer and autoimmune disorders, by targeting and disrupting specific pathways that contribute to disease progression.

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    Research 10 of 1000+

    1. AP-1 and TGFß cooperativity drives non-canonical Hedgehog signaling in resistant basal cell carcinoma Nature Communications · 2020 · 60 citations
    2. Targeting Superficial or Nodular Basal Cell Carcinoma with Topically Formulated Small Molecule Inhibitor of Smoothened Clinical cancer research · 2011 · 63 citations
    3. Stimulation of Hair Growth by Small Molecules that Activate Autophagy Cell reports · 2019 · 88 citations
    4. Game Changers: Blockbuster Small-Molecule Drugs Approved by the FDA in 2024 Pharmaceuticals · 2025 · 8 citations
    5. Drug Repurposing against KRAS Mutant G12C: A Machine Learning, Molecular Docking, and Molecular Dynamics Study International Journal of Molecular Sciences · 2022
    6. New small molecules in dermatology: for the autoimmunity, inflammation and beyond Inflammation Research · 2023 · 9 citations
    7. Case Series: Gene Expression Analysis in Canine Vogt-Koyanagi-Harada/Uveodermatologic Syndrome and Vitiligo Reveals Conserved Immunopathogenesis Pathways Between Dog and Human Autoimmune Pigmentary Disorders Frontiers in Immunology · 2020 · 20 citations
    8. A systematic review of tumor necrosis factor-α blockers, anti-interleukins, and small molecule inhibitors for dissecting cellulitis of the scalp treatment Orphanet Journal of Rare Diseases · 2025
    9. Biologics and Small Molecule Targeted Therapies for Pediatric Alopecia Areata, Psoriasis, Atopic Dermatitis, and Hidradenitis Suppurativa in the US: A Narrative Review Children · 2024 · 8 citations
    10. The Need for Speed and Efficiency: A Brief Review of Small Molecule Antivirals for COVID-19 Frontiers in drug discovery · 2022 · 6 citations
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