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Glossary Skin Tumors

abnormal growths of skin cells, benign or malignant

Skin tumors, also known as skin neoplasms or cutaneous tumors, are abnormal growths of skin cells that can be benign (non-cancerous) or malignant (cancerous). These growths can arise from various types of skin cells, including melanocytes, keratinocytes, and other cell types, and can manifest as moles, warts, or more serious conditions like melanoma and basal cell carcinoma. Early detection and diagnosis are crucial for effective treatment and management.

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Research

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research Expression of ΔNLef1 in mouse epidermis results in differentiation of hair follicles into squamous epidermal cysts and formation of skin tumours

297 citations , January 2002 in “Development”

In this study, repressing β-catenin/Lef1 signalling in mouse epidermis led to progressive hair loss, dermal cysts, and spontaneous skin tumors with sebaceous differentiation, indicating altered keratinocyte differentiation and potential tumourigenic processes.

research Sox9 expression in canine epithelial skin tumors

8 citations , July 2015 in “European journal of histochemistry”

This study found that Sox9 was variably expressed in most canine skin neoplasms, particularly in those originating from the hair follicle's bulge region, suggesting its potential as a stem cell marker.

research Histopathological Study of Epithelial, Melanocytic And Adnexal Tumors Of Skin- A Retrospective Study In A Tertiary Care Centre

August 2021 in “Annals of pathology and laboratory medicine”

This study observed that benign skin tumors were more common than malignant ones, with squamous cell carcinoma being the most frequent type among malignant tumors.

research Skin tumors with matrical differentiation: lessons from hair keratins, beta‐catenin and PHLDA‐1 expression

47 citations , February 2014 in “Journal of Cutaneous Pathology”

This study found that nuclear beta-catenin, LEF1, and PHLDA1 expression was conserved in matrical tumors, suggesting a shared tumorigenesis process involving Wnt pathway activation.

research Lgr6+ stem cells and their progeny in mouse epidermis under regimens of exogenous skin carcinogenesis, and their absence in ensuing skin tumors

7 citations , November 2016 in “Oncotarget”

This study found that Lgr6+ stem cells in mice are not major initiators of UV- or chemically induced skin tumors.

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Community Join

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community My Idea for a possible new hairloss treatment

53 upvotes 6 years ago

Exploring a potential hair loss treatment using the enzyme AKR1C2 to locally reduce DHT levels. Challenges include enzyme delivery through the skin and high production costs, with gene therapy or stem cells suggested as future alternatives.

community Does RU58841 potentially cause cancer?

in Research/Science 1 year ago

RU58841 may pose cancer risks due to its antiandrogen properties and lack of long-term safety data. Using it is considered a high-risk experiment with unknown potential for harm.

community Excessive hair growth from Minoxidil

in Is this regrowth? 434 upvotes 1 year ago

Minoxidil foam and oral finasteride resulted in significant hair regrowth, especially on the hairline, with no side effects from finasteride. The user applied Rogaine 5% for minoxidil.

community Natural sweetener Stevia found to turbocharge male pattern baldness treatment: Mice given Stevia patch had 18 times better absorption of minoxidil and hair coverage of 67.5% in bald areas after just 35 days.

1741 upvotes 8 months ago

Stevia microneedles increased minoxidil absorption and hair growth in mice. The conversation humorously questions the applicability of these results to humans.

community Is Trump no longer on finasteride?

in Finasteride/Dutasteride 258 upvotes 1 year ago

Trump's health report omits finasteride, sparking speculation about whether he stopped using it or switched treatments. Some believe he might not prioritize hair maintenance anymore.

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Clinics

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11
Hair Loss Treatments
Dr. Mehrdad Timourian Skin & Beauty ClinicGorgan · IR

Learn

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learn Vascular Endothelial Growth Factor

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Melatonin

Can melatonin cause side effects on the skin or hair? Melatonin may cause hair loss or thinning in some users, but evidence is limited.

learn Scalp Micropigmentation

Does scalp micropigmentation work on all skin tones and hair colors? Scalp micropigmentation can be customized for various skin tones and hair colors.
Is scalp micropigmentation suitable for people with sensitive skin? Providers say scalp micropigmentation suits most skin types and describe patch tests, hypoallergenic pigments and a skin consultation for sensitive skin. These are provider claims rather than independent safety evidence, and pigment reactions remain a risk.

learn retinol

How does retinol improve scalp health and prepare the skin for other hair growth treatments? Retinol improves scalp health by promoting cellular turnover and reducing congestion.

learn Hyaluronic Acid

Does hyaluronic acid really hydrate the scalp, or is it mainly for skin care? Hyaluronic acid can hydrate the scalp, but its effectiveness may vary.

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Experts

1 / 3 results

36
SMP Specialist
Noelle Skin
Nice, France

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Noelle Skin