176 citations
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August 2000 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” In this study, cross-sex hormone therapy affected hair growth patterns differently, with estrogen reducing hair growth in male-to-female transsexuals and testosterone increasing it in female-to-male transsexuals; however, male typical hair diameters were not fully reached in the latter group after 12 months.
36 citations
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October 2015 in “Journal of Cosmetic Dermatology” In this study, a new apple stem cell extract serum significantly improved signs of skin aging and enhanced cell metabolism in human senescent fibroblasts, showing visible effects after one week of use.
June 2021 in “Current developments in nutrition” In this open-label study, participants reported that the LustrivaTM BH-002 two-step system improved various aspects of hair, skin, and nail health and appearance after three months of use.
6 citations
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September 2019 in “Journal of cosmetic dermatology” This study found that lower serum melatonin levels were associated with increased skin aging grades among individuals in Ulaanbaatar, suggesting melatonin loss may contribute to earlier skin aging.
December 2025 in “Bioengineering” This review explains that dysregulated sebum secretion and composition contribute to acne and impaired skin barriers while highlighting factors like diet and hormones affecting sebaceous activity, and identifies novel molecular targets and model systems for future therapeutic developments.