Search

for
Search:

Research

5 / 1000+ results

research Integrin α3β1 in hair bulge stem cells modulates CCN2 expression and promotes skin tumorigenesis

5 citations , May 2020 in “Life science alliance”

This study found that epidermal-specific deletion of integrin α3β1 significantly reduces papilloma formation in a skin carcinogenesis model by modulating HB stem cell behavior and CCN2 expression.

research Gsdma3 Mutation Causes Bulge Stem Cell Depletion and Alopecia Mediated by Skin Inflammation

54 citations , December 2011 in “American Journal Of Pathology”

This study found that immune-mediated destruction of bulge stem cells is a key factor in the alopecia observed in AE mice, suggesting it as a model for studying primary cicatricial alopecias, particularly lichen planopilaris.

research Vibrissa hair bulge houses two populations of skin epithelial stem cells distinct by their keratin profile

45 citations , December 2007 in “The FASEB journal”

This study demonstrated that hair follicle bulge stem cells can form epidermis in a tissue-engineered skin model, highlighting the significance of K5/K17 filaments in slow-cycling stem cell subsets.

research Keratinocytes-hair follicle bulge stem cells-fibroblasts co-cultures on a tri-layer skin equivalent derived from gelatin/PEG methacrylate nanofibers

11 citations , February 2020 in “Journal of Biomaterials Science Polymer Edition”

This study explored the development of GelMet, an electrospun hybrid nanofiber scaffold made from gelatin and PEG methacrylate, which demonstrated strong mechanical properties and effectively supported cell growth in vitro, suggesting its potential for skin tissue engineering applications.

research Epidermal structure created by canine hair follicle keratinocytes enriched with bulge cells in a three‐dimensional skin equivalent model in vitro: implications for regenerative therapy of canine epidermis

11 citations , January 2013 in “Veterinary dermatology”

This study found that a bulge stem cell-enriched population from canine hair follicles successfully formed interfollicular epidermis in vitro within two weeks, suggesting potential for regenerative canine skin therapies.

View more "skin bulge" in research →

Clinics

3 / 12 results

Learn

5 / 800 results

learn Scalp Micropigmentation

Can scalp micropigmentation work for long hair? Providers say SMP can add the look of density under longer hair, but most say it works best with short hair, and results vary.

learn Fluocinolone

Can long-term use of Fluocinolone affect the health of hair follicles? There is no long-term human trial measuring what topical fluocinolone does to hair follicles; what is documented is the label's warning about skin atrophy with prolonged use, plus a 2007 mouse study suggesting hair-follicle bulge stem cells do not repair steroid-induced atrophy.

learn Melatonin

Can melatonin cause side effects on the skin or hair? No study links melatonin to hair loss; reports are anecdotal. Some users report scalp dryness or irritation from topical products, and a safety review lists mainly mild side effects such as sleepiness and headache.

learn Follistatin

Can follistatin be applied to the skin, and does any form of it treat hair loss? No study shows that follistatin applied to the skin works, and no form of follistatin is an approved or proven hair-loss treatment. Follistatin injections, "research peptides" and gene therapies sold outside regulated trials are unapproved and of unknown safety.

learn Hyaluronic Acid

Does hyaluronic acid really hydrate the scalp, or is it mainly for skin care? Hyaluronic acid improved hydration of facial skin in trials. It has not been tested on the scalp.

View more "skin bulge" in learn →

Community Join

5 / 1000+ results

community [24M] - been taking oral Finasteride 1mg/day for 6 months + been using nanoxidil for 10 months, recently switched to Oral minoxidil 2.5mg daily - Literally no progress. What should I do? I dont have problem with budget, but I dont want to do something useless. Should I undergo PRP + exosomes? Ideas?

in Treatment 3 upvotes 2 years ago

A 24-year-old male has been using oral Finasteride 1mg/day for 6 months and nanoxidil for 10 months, recently switching to oral Minoxidil 2.5mg daily, with no progress. Suggestions include getting a scalp biopsy, consulting a dermatologist, and possibly trying higher doses of oral Minoxidil or switching to dutasteride.

community PP405 is NOT gray market jxl069

in Technology 26 upvotes 8 months ago

PP405 is a safer alternative to JXL069 for hair loss treatment because it penetrates the skin effectively and degrades in the blood, avoiding systemic toxicity. JXL069, when forced into the body, can cause dangerous side effects like lactic acidosis due to its inability to degrade safely.

community Peak efficacy ($18 for a 4 month supply)

in Minoxidil 14 upvotes 1 year ago

The conversation discusses a hair loss treatment regimen involving a homemade topical solution of Minoxidil and Tretinoin, combined with Finasteride and microneedling. Users share advice on Tretinoin application, emphasizing gradual use to avoid skin irritation.

community microneedle, any long term users damage?

in Microneedling 35 upvotes 2 years ago

Microneedling is effective for hair growth, especially when combined with finasteride and minoxidil, but concerns exist about potential long-term skin damage. Users report increased collagen and elastin deposition, but the long-term effects on the scalp remain uncertain.

community Mallia Aesthetics achieves key regulatory steps for novel sCD83-derived ingredient for hair growth

24 upvotes 1 year ago

Mallia Aesthetics has developed MAL-838, a hormone-free product derived from sCD83, which stimulates hair growth without disrupting the skin microbiome. sCD83 promotes hair growth by activating hair follicles and preventing cell death, offering a localized treatment without systemic side effects.

View more "skin bulge" in community →

Experts

1 / 3 results

SMP Specialist
Noelle Skin
Nice, France

Noelle Skin