58 citations
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January 1997 in “Dermatologic Clinics”
Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.
Hair loss treatments, specifically, discussing the effectiveness and side effects of finasteride, minoxidil, and RU58841 in various microdoses. It also includes an updated graph which provides information on how different doses affect DHT levels, scalp skin and serum androgenlevels, as well as hair count.
A user shared progress pictures after 9 months on finasteride, starting with 0.25 mg and increasing to 0.5 mg daily, noting improved hair density, especially at the crown, with initial side effects that resolved after the first month. The discussion includes user experiences with finasteride, concerns about side effects, and alternative treatments like rosemary oil and platelet-rich plasma therapy.
Gut microbiota significantly influences androgen metabolism, impacting hair loss treatments like finasteride. Probiotics, dietary changes, and fecal microbiota transplants may help manage DHT levels and improve hair health.
A 23-year-old has been using finasteride, dutasteride, and spironolactone to combat hair loss and hormonal acne, with mixed results and concerns about side effects. The user is experimenting with spironolactone despite its potential risks, hoping for skin and body hair improvements.
High sugar diets may worsen hair loss by increasing 5α-reductase activity and androgenlevels, especially in women with PCOS. A low sugar diet might reduce scalp DHT levels, similar to finasteride, but genetics also significantly influence hair loss.