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Glossary Signaling Molecules

chemicals that cells use to communicate and coordinate functions

Signaling molecules are chemicals that cells use to communicate with each other. They can be hormones, neurotransmitters, or other types of molecules that bind to specific receptors on target cells, triggering a response. This process is crucial for coordinating various biological functions, such as growth, immune responses, and hair follicle development.

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Research

5 / 1000+ results

research Transcutaneous electrical acustimulation promotes wound healing in mice by modulating signaling molecules and mitochondria function

1 citations , February 2025 in “Archives of Dermatological Research”

This study found that transcutaneous electrical acustimulation aided wound healing in mice by enhancing expression of proteins related to signaling pathways, stress recovery, and mitochondrial function.

research Molecular signaling in feather morphogenesis

85 citations , October 2006 in “Current opinion in cell biology”

This article reviews advances in feather development and regeneration, including pattern formation, stem cell biology, and evolution, but presents no new experimental results.

research The Molecular Mechanism of Natural Products Activating Wnt/β-Catenin Signaling Pathway for Improving Hair Loss

November 2022 in “Life”

This review discusses the role of the Wnt/β-catenin pathway in hair follicle development and how natural products that activate this signaling could be used to treat hair loss, but it reports no new experimental results.

research Molecular Mechanisms and Targeted Therapeutics in Androgenetic Alopecia: From Signaling Pathways to Regenerative Approaches

May 2026 in “Premier journal of science.”

This review examines androgenetic alopecia, detailing its causes and current treatments, but reports no new clinical results; the authors emphasize understanding its complexity for personalized therapy development.

research Corrigendum to: Low Molecular Weight Collagen Peptide (LMWCP) Promotes Hair Growth by Activating the Wnt/GSK-3β/β-Catenin Signaling Pathway

April 2024 in “Journal of microbiology and biotechnology”

The authors will correct the table to show the right antibody information.

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Community Join

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community Any interesting future treatments around the corner

7 upvotes 6 years ago

Potential future hair loss treatments include stem cell therapy, Clascosterone (Breezula), Amplifica's signaling molecules, Botox, and dutasteride mesotherapy. Some treatments are promising but expensive, like Tsuji's technique, while others, like Botox, show unexpected results.

community IGF-1 and Peptides? Miracle molecule waiting to be found

10 upvotes 1 year ago

The conversation discusses potential hair loss treatments focusing on stimulating IGF-1 at the follicle level using growth-factor cocktails and engineered peptides, such as Acetyl Tetrapeptide-3, Copper Tripeptide-1, Oligopeptide-20, Thymosin-β4, and Palmitoyl Tetrapeptide-7. It suggests that device-assisted delivery methods like microneedling may enhance effectiveness.

community Korean scientists breakthrough in hair regeneration targeting CXXC5 protein and WNT Signaling Pathway

53 upvotes 8 years ago

A potential non-invasive topical treatment targeting the WNT Signaling Pathway for hair regeneration is being researched, with positive results on human hair follicle cells. Current effective treatments for hair loss include Minoxidil, finasteride, and hair transplantation.

community Did Scientists Just Cure Baldness? UCLA’s New Molecule Could Revolutionize Hair Growth

559 upvotes 1 year ago

PP405 shows promise for hair growth but may need continuous use like Minoxidil. Current treatments include Minoxidil, finasteride, and dutasteride, with skepticism about a true cure due to financial interests.

community Everything you ever wanted to know about Pelage Pharma's PP405: how it works and what to expect

126 upvotes 2 months ago

PP405 may encourage earlier hair growth and slightly increase visible hair count but does not reverse hair follicle miniaturization in male pattern baldness. It does not address damage to the dermal papilla or broken Wnt signaling.

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Learn

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learn SCUBE3

a signaling molecule from dermal papilla cells being actively researched

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn PP405

mitochondrial pyruvate carrier (MPC) inhibitor by Pelage in early trials

learn Stem Cell Factor

learn sh-Polypeptide-7

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