1 citations
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July 2023 in “Cosmetics” This study found that a novel shampoo formulation effectively delivers caffeine to hair follicles, with 8–9% of absorbed caffeine reaching the follicles, suggesting it may support hair retention by enhancing antioxidant activity.
93 citations
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January 2007 in “Skin Pharmacology and Physiology” In this study, caffeine applied in a shampoo penetrated hair follicles faster and more effectively than through the skin surface within the first 20 minutes.
This study conducted a pre-formulation evaluation of a caffeine shampoo for androgenic alopecia treatment, finding that the formulation remains stable under various conditions, suggesting its viability for compounding.
5 citations
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October 2020 in “Giornale italiano di dermatologia e venereologia” This study found that a phyto-caffeine-containing shampoo was more effective than a control shampoo in reducing hair loss and improving hair strength in women with androgenetic alopecia over a 6-month period.
26 citations
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December 2009 in “Laser Physics” This study observed that caffeine-containing shampoo can penetrate hair follicles to a depth of approximately 200 μm and remains detectable even after 24 hours, suggesting a potential long-term reservoir effect.