research 50570 Irritation and sensitization potential of approved topical and transdermal delivery systems – A retrospective study
Generic topical and transdermal systems usually cause minimal irritation or sensitization.
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research A hair-follicle reconstructed in vitro immunocompetent skin model for prediction of the sensitizing potential of chemicals
The study introduced an advanced skin model, ImmuSkin-MT, which effectively distinguished between different strengths of skin sensitizers by mimicking the interaction of immune cells in skin tissue.
research Analysis of Common Treatment Drugs and Allergen Sensitization in Hair Loss Patients
This study examined the sensitization potential of common hair care products and found that certain ingredients, like cobalt chloride and nickel sulfate, frequently cause allergic reactions in individuals with hair diseases, providing essential insights for personalized treatment strategies.
research Sensitisation to ethylhexyl salicylate: Another piece of the frontal fibrosing alopecia puzzle
In this study, sensitization to ethylhexyl salicylate was found in 27.3% of patients with frontal fibrosing alopecia, suggesting it may be a potential contact allergen for this condition.
research Indications for Peripheral and Central Sensitization in Patients With Chronic Scalp Pain (Trichodynia)
This study found that trichodynia is associated with both peripheral and central sensitization, potentially linked to hair cycle abnormalities and chronic pain through proinflammatory agents.
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5 / 6 resultscommunity New Research- Creatine Increasing Scalp DHT Without Corresponding Serum DHT Increase
Creatine may increase scalp DHT without affecting serum DHT, potentially speeding up male pattern baldness (MPB) for those genetically prone. Treatments mentioned include Minoxidil, finasteride, and RU58841.
community Study: There is 70x Higher Unconjugated DHT in Feces Compared To Blood Levels in Young Adults - Gut Microbiota Manages DHT Recycling and Metabolism
Gut microbiota significantly influences androgen metabolism, impacting hair loss treatments like finasteride. Probiotics, dietary changes, and fecal microbiota transplants may help manage DHT levels and improve hair health.
community Can we stop fear mongering with finasteride
Finasteride is effective for hair loss but can cause sexual dysfunction and mental health issues in some users, leading to a polarized debate on its risks. Some switch to alternatives like Dutasteride or topical treatments to avoid side effects.
community Dht kills hair, but no one says why?
DHT affects hair follicles, contributing to hair loss, but the exact mechanism is unclear. Treatments like finasteride and minoxidil are used to manage hair loss, though they may have side effects and varying effectiveness.
community Quit finasteride after 15+ years
A user stopped finasteride after 15 years due to severe side effects, which improved after quitting. They maintained most of their hair and are considering alternatives like topical treatments or RU58841.
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