TLDR Patch testing is crucial to reduce allergic reactions in hair loss treatments.
The study examined allergen sensitization in 196 hair loss patients through patch tests, focusing on common hair loss types and treatment drugs. Results indicated that 7 cosmetic ingredients, including preservatives and metals, were prone to sensitization. Notably, dodecyl polyglucoside had a 10.20% positivity rate, while metal allergens cobalt chloride and nickel sulfate had rates of 56.63% and 32.65%. Topical medications like ketoconazole lotion showed a 50.00% positivity rate. Minoxidil formulations had significant sensitization potential, with rates decreasing when combined with hydrocortisone. The study underscores the importance of patch testing to minimize allergic reactions and improve treatment compliance, advocating for personalized treatment approaches. Limitations include potential errors from varying concentrations, suggesting a need for larger-scale studies.
16 citations
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December 2016 in “Skin appendage disorders” Nickel, cobalt, balsam of Peru, fragrance mix, carba mix, and propylene glycol are common allergens causing scalp contact dermatitis.
397 citations
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February 2004 in “British Journal of Dermatology” Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.
137 citations
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May 1984 in “Journal of Investigative Dermatology” Minoxidil increases blood flow in balding scalps, possibly reversing hair loss.
148 citations
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December 2018 in “Journal of autoimmunity” Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.
4 citations
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November 2018 in “JAAD case reports” Alopecia areata can sometimes appear as a straight line of hair loss instead of round patches.
May 2018 in “Journal of cosmetology & trichology” Combining platelet-rich plasma therapy with prostaglandin-F eye drops can significantly regrow hair in alopecia universalis.
110 citations
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December 2013 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” Alopecia areata is a genetic and immune-related hair loss condition that is often associated with other autoimmune diseases and does not typically cause permanent damage to hair follicles.
