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Glossary Sebum Production

process where skin glands release oil to protect skin

Sebum production, also known as sebum secretion or oil production, is the process by which sebaceous glands in the skin produce and release an oily substance called sebum. This natural oil helps to lubricate and protect the skin and hair, maintaining moisture and providing a barrier against external contaminants. Overproduction of sebum can lead to oily skin and contribute to conditions like acne, while underproduction can result in dry, flaky skin.

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5 / 1000+ results

community For people with overly oily hair, does topical finasteride/dutasteride/antiandrogens (like RU or Pyrilutamide) reduce sebum overproduction?

in Finasteride/Dutasteride 6 upvotes 3 years ago

The conversation discusses whether topical finasteride, dutasteride, or antiandrogens like RU58841 can reduce sebum overproduction as an early indicator of their effectiveness in treating hair loss. It suggests that while hair growth may take months to observe, a decrease in oiliness could be a quicker sign of a product's action.

community How to deal with overproduction of sebum?

10 upvotes 1 month ago

The user is experiencing diffuse thinning and excessive sebum production, considering Accutane as a potential solution after trying dutasteride and oral minoxidil without success. Other users suggest treatments like Nizoral shampoo, finasteride, beclomethasone dipropionate lotion, and topical androgen receptor inhibitors.

community DHT Harms Scalp Microbiome: DHT Itch is REAL

413 upvotes 1 year ago

Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

community Double Shampooing Everyday. Safe or not?

in Chat 8 upvotes 7 months ago

Double shampooing daily is safe and helps manage oily scalp and dandruff without causing hair loss. Accutane is considered for reducing sebum production despite potential temporary hair loss.

community Anyone on Dutasteride have reduced scalp oil?

in Finasteride/Dutasteride 13 upvotes 1 year ago

Dutasteride may reduce scalp oil and itchiness more effectively than finasteride, with some users experiencing drier skin and improved hair thickness. Users report varying results, with some noticing benefits after switching from finasteride to dutasteride, while others use a combination of treatments including minoxidil.

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Research

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research Updated Management of Atrophic Post Acne Scars: Review Article

October 2021 in “The Egyptian Journal of Hospital Medicine ”

This study concluded that combination therapies often yield better results for treating atrophic post-acne scars than single treatments.

research 896 Androgens activate lipogenesis through an AKT-independent mTOR pathway stimulation and a limitation of autophagy in an androgen-sensitive sebocyte cell line

April 2019 in “Journal of Investigative Dermatology”

This study demonstrates that DHT-induced lipid synthesis in sebocytes involves the mTOR pathway, suggesting mTOR inhibitors may help modulate androgen-dependent sebum overproduction.

Hyperandrogenism Caused by Leydig Cell Tumor of the Ovary

research Hiperandrogenismo causado por tumor de células de Leydig de ovario

January 2020

This case report describes a 65-year-old postmenopausal woman with hyperandrogenism caused by a non-malignant ovarian Leydig cell tumor, which is a rare cause of virilization.

research Androgen Conjugates: Physiology and Clinical Significance

54 citations , February 1993 in “Endocrine reviews”

This review examines the physiological role of androgen conjugates in cutaneous androgen metabolism and questions their association with hirsutism, without presenting new clinical findings.

Changes in Serum Free Testosterone, Sleep Patterns, and 5-Alpha-Reductase Type I Activity Influence Sebum Excretion in Female Subjects

research Changes in serum free testosterone, sleep patterns, and 5‐alpha‐reductase type I activity influence changes in sebum excretion in female subjects

10 citations , August 2014 in “Skin research and technology”

This study found that variations in sleep patterns, free testosterone, and 5-alpha-reductase type 1 activity are associated with changes in sebum excretion in women, which may contribute to variability in acne studies.

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Learn

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learn Baicapil

Could a daily serum with Baicapil help revive dormant hair follicles before it’s too late? Yes, a daily serum with Baicapil may help revive dormant hair follicles.

learn Bimatoprost

Can a lash-growth serum like bimatoprost actually work for your scalp? Bimatoprost (Latisse) is approved for eyelashes, not the scalp; two Allergan phase 2 trials in men with androgenetic alopecia posted results to ClinicalTrials.gov but were never published in a peer-reviewed journal, so scalp use remains off-label and experimental.

learn Hyaluronic Acid

What’s the difference between using hyaluronic acid as a serum on the scalp versus taking it as a supplement? Hyaluronic acid serum hydrates the scalp surface, while supplements may support overall hair health.

learn Exosomes

Are exosomes applied as a serum, an injection, or combined with other hair treatments? Exosomes are typically injected directly or combined with other hair treatments.

learn Rapamycin

Are there any visible side effects when using rapamycin cream or serum on the scalp? Visible side effects may include skin irritation or redness when using rapamycin on the scalp.

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