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The 5alpha-Reductase Type 1, But Not Type 2, Gene Is Expressed in Anagen Hairs Plucked from the Vertex Area of the Scalp of Hirsute Women and Normal Individuals

research The 5alpha-Reductase Type 1, But Not Type 2, Gene Is Expressed in Anagen Hairs Plucked from the Vertex Area of the Scalp of Hirsute Women and Normal Individuals

17 citations, October 2003 in “Brazilian Journal of Medical and Biological Research”

The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.

research Update on Idiopathic Hirsutism: Diagnosis and Treatment

6 citations, July 2013 in “Acta Clinica Belgica”

The document concludes that combination therapy is most effective for treating excessive hair growth in women with idiopathic hirsutism, and more research is needed to understand the condition.

research Pumpkin Seed Oil-Loaded Niosomes for Topical Application: 5α-Reductase Inhibitory, Anti-Inflammatory, and Anti-Hair Loss Effects

7 citations, July 2022 in “Pharmaceuticals”

Pumpkin Seed Oil in niosomes may help treat hair loss and improve hair growth.

research Analysis of Genetic Polymorphisms of Steroid 5α-Reductase Type 1 and 2 Genes in Korean Men with Androgenetic Alopecia

15 citations, April 2003 in “Journal of Dermatological Science”

Gene differences may affect baldness treatment response in Korean men.

research 5α-Reductase Type 2 Gene Variant Associations with Prostate Cancer Risk, Circulating Hormone Levels, and Androgenetic Alopecia

57 citations, February 2007 in “International Journal of Cancer”

A49T gene variant linked to higher prostate cancer risk, lower hormone levels, and slightly reduced balding risk.

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Community Join

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community Anyone experienced weight gain on dutasteride?

in Finasteride/Dutasteride 6 upvotes 2 years ago

Dutasteride can lead to increased cholesterol and liver fat. The user is reconsidering its use due to high cholesterol and lipid levels despite a healthy lifestyle.

community CRISPR Is Curing People Right Now. Genetic Hair Loss is Next?

in Technology 107 upvotes 5 months ago

CRISPR shows promise for treating hair loss by targeting specific genes. Current treatments include Minoxidil and finasteride, but CRISPR could offer a more precise solution, though it is still expensive and in early stages.

community My hair after 3 steroid cycles

in Progress Pictures 24 upvotes 8 months ago

A user shared their hair progress after three steroid cycles, using 5% minoxidil and 100mg RU58841 daily. They are considering a hair transplant due to paranoia about shedding.

community M44 Hairloss Trichotest and Finasteride

in Finasteride/Dutasteride 6 upvotes 1 year ago

User received Trichotest results not recommending Finasteride. They are on Oral Minoxidil 2.50 and considering adding Finasteride.

community Pirfenidone - The answer to fibrosis and baldness

in Treatment 19 upvotes 3 years ago

Pirfenidone is suggested to treat fibrosis and baldness by blocking inflammation markers and reducing collagen. It is also available as a gel for scar removal.

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