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Generation of an Integration-Free Human Induced Pluripotent Stem Cell Line MUSIi010-A from Occipital Scalp Fibroblasts of a Male Patient with Androgenetic Alopecia

research Generation of an integration-free human induced pluripotent stem cell line MUSIi010-A from occipital scalp fibroblasts of a male patient with androgenetic alopecia

June 2019 in “Stem Cell Research”

This study established a pluripotent stem cell line from a patient with androgenetic alopecia, which can potentially be used to study the disease's pathological mechanisms.

research Altered FGF expression profile in human scalp-derived fibroblasts upon WNT activation: implication of their role to provide folliculogenetic microenvironment

17 citations , September 2020 in “Inflammation and Regeneration”

In this study, researchers found that WNT activation influenced FGF expression in human scalp-derived fibroblasts, with mouse model results showing FGF9 increased hair follicle number and diameter, while FGF7 reduced diameter.

research Human Scalp Dermal Papilla and Fibrous Sheath Cells have a different expression profile of Matrix Metalloproteinases in vitro when compared to Scalp Dermal Fibroblasts

9 citations , August 2005 in “Archives of Dermatological Research”

Scalp dermal papilla and fibrous sheath cells have different MMP expression than scalp dermal fibroblasts.

research 259 Scalp hair follicle dermal sheath fibroblasts express genes associated with promotion of skin integrity/wound healing and prevention of autoimmune responses in Recessive Dystrophic Epidermolysis Bullosa

November 2024 in “Journal of Investigative Dermatology”

Scalp hair follicle cells help protect and heal skin in certain skin conditions.

research Age-Related Changes in Female Scalp Dermal Sheath and Dermal Fibroblasts: How the Hair Follicle Environment Impacts Hair Aging

14 citations , December 2020 in “Journal of Investigative Dermatology”

This study observed that aging leads to significant structural and biological changes in the scalp's hair follicle environment in women, which may affect hair growth.

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community Topical Finasteride Doesn't Directly Reduce 5ar Enzyme on Scalp

in Finasteride/Dutasteride 72 upvotes 3 years ago

Topical Finasteride doesn't directly reduce 5ar enzyme on scalp and has the same mechanism as oral, needing to go through the liver. Users debate the accuracy of this information and discuss various studies and experiences.

community Occipitalis Muscle Tension Theory

13 upvotes 7 months ago

Scalp tension from the occipitalis muscle is theorized to contribute to hair loss, but most believe DHT and genetics are the main causes. Treatments like finasteride and minoxidil are considered more effective than addressing scalp tension.

community The Real Reason For Hair Loss?

8 months ago

Hair loss is linked to scalp fibrosis and tension, which result from chronic mechanical stress and androgenic signaling. Treatments include blocking androgens with finasteride, promoting hair growth with topical minoxidil, and improving scalp mobility through exercises.

community Got my Oleic fatty acid they used in Korean study. Fuck you mice!

247 upvotes 7 months ago

Oleic acid and microneedling are being explored for hair regrowth, but results are mixed. Addressing DHT and fibrosis is crucial, with treatments like finasteride, minoxidil, and scalp massage also discussed.

community Hair routine (all info listed)

4 upvotes 3 years ago

The user shares a hair loss routine involving finasteride, B-Complex vitamins with biotin, pumpkin seed oil, apple cider vinegar, aloe vera, honey water, olive oil, and tea tree oil. They emphasize avoiding shampoo and using natural rinses to maintain scalp health and promote hair growth.

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