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research Light‐based home‐use devices for hair removal: Why do they work and how effective they are?

15 citations , January 2019 in “Lasers in surgery and medicine”

This review reported that home-use laser and intense pulsed light devices effectively reduce hair with significant efficacy and safety, showing 80% hair reduction one year post-treatment, although results can vary for darker skin types and compared to professional devices.

research Alopecia areata in children: an overview of clinical features and recent treatment options

December 2022 in “Rossijskij žurnal kožnyh i veneričeskih boleznej”

This source highlights that the incidence of alopecia areata is increasing among children, and while corticosteroids and Janus kinase inhibitors show potential effectiveness and safety, they remain unapproved by the FDA for pediatric use.

research Evaluation of clinical and trichoscopic features of androgenetic alopecia and its relation with disease severity

August 2019 in “Journal of The American Academy of Dermatology”

PFD patch helps laser tattoo removal, trichoscopy diagnoses AGA, and serum boosts SOD activity.

research Clinical Features and Current Therapeutic Approaches to Monilethrix: A Systematic Review

May 2025 in “Pediatric Dermatology”

This systematic review identified topical and oral minoxidil as the most effective treatments for monilethrix, but noted the varying efficacy of oral retinoids and other treatments.

research Featured Cover

May 2025 in “Journal of Cosmetic Dermatology”

This pilot study by Samuel Jellard et al. investigated a novel electrotrichogenic device for hair growth in men with androgenetic alopecia. Results of the study are not reported, as the abstract only references the article's focus.

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Community Join

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community Genuine question about VDPHL01's long term safety that I haven't seen discussed here

in Research/Science 28 upvotes 4 months ago

Concerns about the long-term safety of VDPHL01, an extended-release minoxidil, due to potential risks similar to Cantu syndrome, were raised, highlighting the lack of monitoring for chronic connective tissue changes. The conversation suggests that while the treatment may improve hair growth, it could lead to issues not detected in short-term trials.

community What has the evidence been on side effects with CB?

4 upvotes 6 years ago

Clascoterone (CB) shows an excellent safety profile with no serious side effects, but its effectiveness may decline after six months, making it more suitable as an adjunct treatment with finasteride and minoxidil rather than a standalone solution. Some argue it could be better than finasteride due to its protection against testosterone, but its long-term efficacy remains debated.

community Dutasteride at 21 years old. Is it safe?

in Finasteride/Dutasteride 12 upvotes 2 years ago

A 21-year-old individual questioning the safety and potential side effects of using Dutasteride for hair loss, after Finasteride and RU58841 had limited effect. The responses vary, with some users suggesting it's safe and others advising to check hormone levels before proceeding.

community Microneedling, some people seem to permanently lost their hair. Confused

in Microneedling 35 upvotes 1 year ago

Microneedling can aid hair regrowth but poses risks like permanent hair loss if not done properly. Combining it with minoxidil, finasteride, and tretinoin, while ensuring proper sterilization and technique, is crucial for safety and effectiveness.

community Pelage Pharmaceuticals’ PP405 and its Impact on Follicular Regeneration to be Presented at the American Academy of Dermatology (AAD) Annual Meeting 2026 28th march

30 upvotes 5 months ago

Pelage Pharmaceuticals' PP405 aims to treat hair loss by reactivating dormant hair follicle stem cells, showing promising results in early trials. The company plans to present their findings at the American Academy of Dermatology Annual Meeting in 2026.

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Learn

10 / 801 results

learn Hair Multiplication

extract, clone, and reinsert your own hair cells

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn Beta Polypeptide

learn Overview

learn Thymosin Beta 4

learn Latanoprost

Can latanoprost be safely applied to the scalp, or is it only for eyelashes? Latanoprost is not approved for use on the scalp and its safety there has not been established: the only human scalp evidence is one 24-week pilot trial in 16 men, and clinicians flag irritation, skin darkening and unknown absorption over a large area as open risks.

learn Setipiprant

Can Setipiprant be used safely by women or people undergoing gender transition? Setipiprant's safety for women and those in transition is not well-studied.

learn sh-Polypeptide-7

Are there any safety concerns or allergic reactions associated with sh-Polypeptide-7 in topical hair products? There are no published human studies on sh-Polypeptide-7 itself, so its safety is unestablished; research on cosmetic peptides as a class reports low irritation and rare allergy, and dermatologists advise patch testing a new scalp product.

learn Hydrocortisone

How do you safely apply hydrocortisone cream or lotion to the scalp without overusing it? The over-the-counter hydrocortisone label sets the limits: a thin film on the affected patch, no more than three or four times a day, and no longer than seven days without a doctor's direction — and the scalp absorbs corticosteroids more than most skin, so prolonged use raises the risk of thinning skin.

learn Spironolactone

Who can safely use spironolactone for hair thinning and androgen-related hair loss? Women with androgen-related hair loss can safely use spironolactone under medical supervision.

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