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    Glossary S100 Proteins

    calcium-binding proteins involved in cell regulation and signaling

    S100 Proteins are a family of calcium-binding proteins involved in various intracellular and extracellular functions, such as regulation of protein phosphorylation, enzyme activities, and cell growth and differentiation. They are implicated in several diseases, including cancer, neurodegenerative disorders, and inflammatory conditions, making them significant both in basic biological research and clinical diagnostics.

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    1. Expression of Calcium-Binding S100 Proteins A4 and A6 in Regions of the Epithelial Sac Associated with the Onset of Hair Follicle Regeneration Journal of Investigative Dermatology · 2001 · 72 citations
    2. The Roles of S100 Proteins and RAGE in Melanoma InTech eBooks · 2011 · 5 citations
    3. S-100 Protein Immunoreactivity in the Upper Eyelid of the Sheep Ovis aries Journal of Molecular Histology · 2004 · 2 citations
    4. Identification of Trichohyalin-Like 1, an S100 Fused-Type Protein Selectively Expressed in Hair Follicles Journal of Investigative Dermatology · 2011 · 27 citations
    5. Trichohyalin-Like Proteins Have Evolutionarily Conserved Roles in the Morphogenesis of Skin Appendages Journal of Investigative Dermatology · 2014 · 68 citations
    6. S100 signaling in hair follicle biology: emerging mechanistic insights and therapeutic opportunities Journal of Molecular Histology · 2026
    7. Human Trichohyalin Gene Is Clustered with the Genes for Other Epidermal Structural Proteins and Calcium-Binding Proteins at Chromosomal Locus 1q21 1993
    8. Characterization of the cysteine-rich calcium-binding S100A3 protein from human hair cuticles Biochemical and biophysical research communications · 2002 · 17 citations
    9. Isolation and Characterization of Human Repetin, a Member of the Fused Gene Family of the Epidermal Differentiation Complex Journal of Investigative Dermatology · 2005 · 77 citations
    10. Human hair follicle biomagnetism: potential biochemical correlates 2015 · 8 citations
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