October 2015 in “Elsevier eBooks” Pramipexole can cause side effects like dizziness, sleepiness, hallucinations, and low blood pressure, and it's important to educate patients and keep doses low.
June 2016 in “CRC Press eBooks” This article discusses the role of hyperarousal and brain activity in insomnia and its potential link to sleep disturbances in depression, but it reports no new empirical findings.
January 2020 in “Skinmed” This study found that finasteride use was significantly associated with reports of obstructive sleep apnea and insomnia compared to other drugs in the FAERS database.
April 2023 in “Tropical Animal Health and Production” Giving melatonin to sheep before the non-breeding season can improve their chances of reproducing in northwest Mexico.
58 citations
,
January 2015 in “Journal of the American Academy of Dermatology” Pioglitazone may help treat lichen planopilaris, but more research is needed.
6 citations
,
December 2008 in “Clinics in Dermatology” This study presents four cases of delusions of parasitosis and introduces escitalopram as a potential therapy, highlighting its fewer side effects compared to the commonly used pimozide.
October 2016 in “Iranian journal of psychiatry and behavioral sciences” This case study reports instances of hair loss in two patients taking sertraline, suggesting that even low doses of SSRIs might cause this rare side effect, which could impact treatment adherence.
January 2017 in “ScholarWorks - WMU (Western Michigan University)” This case report suggests that Citalopram may cause reversible hair loss in some patients, as evidenced by hair regrowth after discontinuing the drug.
66 citations
,
January 2008 in “Pharmacology Biochemistry and Behavior” AC-5216 reduces anxiety in mice through neurosteroids affecting GABAA receptors.
20 citations
,
August 2008 in “Journal of Medical Case Reports” This case report describes a probable hypersensitivity reaction to a single intravenous dose of ondansetron, highlighting the need for cautious use, especially in outpatient settings.
September 2024 in “Revista Científica de Salud BIOSANA” This systematic review explored the potential of cetirizine, an anti-inflammatory antihistamine, as a complementary treatment for androgenetic alopecia, reporting that it might help prevent hair follicle miniaturization by reducing inflammation and modulating immune activity, without notable side effects.
November 2023 in “Curēus” This review examines melatonin's role in managing PCOS and its potential to improve hormonal balance, oxidative stress, sleep quality, and mood, but reports no new clinical results.
This study found that finasteride use was significantly associated with the reporting of obstructive sleep apnea and insomnia compared to all other drugs in the FAERS database.
49 citations
,
September 2016 in “Genes Brain & Behavior” In this study, a deficiency in the zinc finger protein Zfp462 in mice led to anxiety-like behaviors and excessive self-grooming, providing a new model for studying anxiety disorders.
32 citations
,
September 2010 in “Stress” This study found that suppressing allopregnanolone production in late gestation fetal sheep altered CNS activity and behavioral responses to transient asphyxia, effects mitigated by an analog co-infusion.
December 2023 in “Magna Scientia Advanced Research and Reviews” This study proposes that combining trazodone and clomiphene citrate could potentially restore libido synaptic circuits and treat post-finasteride syndrome, which involves persistent sexual dysfunction after discontinuing finasteride treatment.
3 citations
,
May 2025 in “Archives of Gynecology and Obstetrics” In this study, researchers reported that women with polycystic ovary syndrome in a German-speaking population had higher probabilities of depression, anxiety, sleep disorders, and obstructive sleep apnea, all associated with BMI and insulin resistance.
109 citations
,
March 2011 in “Journal of controlled release” This study found that econazole nitrate delivered via MPEG-dihexPLA micelles significantly increased skin deposition compared to Pevaryl® cream, potentially enhancing drug bioavailability and clinical efficacy.
May 2022 in “Research Square (Research Square)” Melatonin improved sheep reproduction, being more beneficial and cost-effective in males.
18 citations
,
August 2011 in “Clinical Drug Investigation” This study found that a combination of low-dose isotretinoin and oral azithromycin pulse effectively treats severe acne with an acceptable side effect profile and relatively low relapse rates.
13 citations
,
April 2019 in “International journal of molecular sciences” This article reviews the potential of Acyzol, a zinc-containing drug, to treat and prevent zinc deficiency conditions, but it reports no new clinical findings.
8 citations
,
April 2006 in “Acta dermato-venereologica” Dovobet ointment used overnight effectively reduces scalp psoriasis severity and itch.
2 citations
,
April 2022 in “Sleep and Breathing” This study found an association between sleep disturbances and androgenetic alopecia in men, with severe AGA linked to shorter sleep duration, poorer sleep quality, and higher STOP-BANG scores.
January 2013 in “Chinese Journal of Hospital Pharmacy” This study developed a precise and sensitive HPLC-MS/MS method for analyzing the pharmacokinetics of perospirone hydrochloride in human plasma, establishing it as suitable for clinical studies.
March 2023 in “Seminars in reproductive medicine” This review discusses the link between polycystic ovary syndrome and sleep problems, primarily obstructive sleep apnea, and calls for more research on other sleep disturbances in affected women and adolescent girls.
June 2025 in “Medicine theory and practice” This study compared the effectiveness of combined oral contraceptives and antiandrogens for treating women with polycystic ovarian syndrome in late reproductive age.
50 citations
,
January 2018 in “Acta physiologica” This study found that four days of simulated night shift work in healthy adults reduced insulin sensitivity, suggesting a potential increased risk of type 2 diabetes.
10 citations
,
May 2020 in “Advances in Polymer Technology” This study found that melatonin-loaded nanoparticles improved antidepressant effects and HPA axis regulation in pinealectomized rats, compared to free melatonin, through controlled-release properties.
October 2025 in “Pharmaceutical Development and Technology” In this study, cetirizine hydrochloride was formulated into niosomal and cubosomal gels, showing potential for off-label use in treating androgenic alopecia due to effective skin permeation and acceptable safety profiles; cubosomal gels exhibited superior permeation compared to niosomal gels.
2 citations
,
May 2021 in “Clinical Pharmacology in Drug Development” This phase 1 study reported that after administering supratherapeutic doses of cortexolone 17α‐propionate, a topical antiandrogen intended for hair loss treatment, there was no effect on the QTc interval, indicating no measurable cardiac safety concerns in the concentration range tested.