July 2026 in “Anales de la Facultad de Ciencias Médicas (Asunción)” In this case report, azathioprine was linked to anagen effluvium in a 36-year-old woman after two weeks of use; hair regrowth occurred once the drug was stopped and minoxidil treatment was started.
26 citations
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January 2004 in “Journal of Toxicology Clinical Toxicology” This case report details a 43-year-old woman who survived severe multiorgan injury from accidental Colchicum autumnale poisoning, resulting in ongoing muscle weakness and intermittent hair loss three years after the incident.
This study found that incorporating Aloe vera and celery extract into water or oil microemulsions promoted hair growth in rats, with the water-in-oil formulation showing faster initial results.
December 2025 in “Indian Journal of Case Reports” This case report highlights an unusual instance of azathioprine potentially triggering rapid alopecia areata and bone marrow suppression in a patient with chronic spontaneous urticaria, with improvement seen after stopping the drug.
26 citations
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November 2002 in “Planta medica” In this study, the methanol extract of Cercidiphyllum japonicum heartwood was found to stimulate the proliferation of mouse hair epithelial cells, with several isolated compounds showing significant proliferative activities.
October 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” This study experimentally validated Lockhart's viscoplastic framework for tip growth in Arabidopsis root hairs by demonstrating alignment with observed growth rates and estimating yield turgor pressure and cell wall viscosity, offering a methodology adaptable to other species and conditions.
November 2025 in “Naukovij vìsnik veterinarnoï medicini” This study found that applying aqueous bay leaf extract to skin graft wounds in rabbits reduced inflammation and improved tissue regeneration, leading to enhanced healing compared to untreated controls, particularly in terms of collagen organization, fibrosis, and inflammation modulation over a 21-day period.
4 citations
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January 2020 6 citations
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April 2010 in “International Journal of Advances in Scientific Research” This article reviews the traditional uses, active compounds, and potential medicinal properties of Wedelia biflora and Wedelia chinesis, particularly focusing on their anti-inflammatory and wound healing activities, but reports no new experimental results.
Minoxidil can cause hair growth as a side effect.
26 citations
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September 1999 in “Canadian Journal of Botany” This study found that a recessive mutation in the RHD4 gene of Arabidopsis thaliana leads to slower and more variable tip growth in seedling root hairs, resulting in shorter and wider hairs than in wild-type plants.
February 2026 in “The Animal Biology” In this animal study, Hirudo verbana leech extract significantly improved hair follicle regeneration and accelerated wound healing in rats, demonstrating potential as a safe and effective agent for skin repair due to its bioactive compounds with regenerative and anti-inflammatory properties.
February 2024 in “Oriental Journal of Chemistry/Oriental journal of chemistry” This review reports various ethnomedicinal uses, phytochemical components, and potential pharmacological effects of Eclipta alba, highlighting benefits like wound healing and neuroprotection, though it underscores the need for further mechanism-based studies and clinical trials.
December 2025 in “CyberLeninK (CyberLeninka)” This study evaluated the phytochemical composition of Tamarix aphylla (L.) Karst., revealing the presence of bioactive compounds like alkaloids, flavonoids, and phenolics, which may contribute to its various medicinal properties.
13 citations
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January 2014 in “Aesthetic Surgery Journal” This study found that Cyperus rotundus essential oil is as effective as the Alexandrite laser in reducing the growth of unwanted axillary hair, with notable effectiveness in decreasing white hair growth.
April 2016 in “Journal of Investigative Dermatology” This study found that topical phenylephrine, an α1-AR agonist, significantly reduced hair shedding and increased epilation force threshold in women experiencing traction alopecia during cosmetic procedures.
January 2019 in “Journal of Case Reports and Scientific Images” This case report describes the treatment of a 12-year-old female with Alopecia Areata using oral azathioprine.
27 citations
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August 1984 in “Experimental and Molecular Pathology” 82 citations
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January 2011 in “New Phytologist” This study demonstrated that AtVLN4 plays a role in root hair growth by regulating actin organization in a calcium-dependent manner.
July 2026 in “International Journal of Drug Delivery Technology” In this case report, a 14-year-old girl developed azathioprine-induced anagen effluvium, highlighting it as a rare but reversible side effect with prompt drug withdrawal leading to significant hair regrowth.
2 citations
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June 2025 in “International Journal of Molecular Sciences” In this study, Carthamus caeruleus root juice exhibited in vitro anti-inflammatory effects by stabilizing human erythrocyte membranes and inhibiting albumin denaturation, as well as showing potential inhibition of COX-2 through in silico analysis; however, further research is needed to confirm efficacy and mechanisms.
7 citations
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May 2018 in “Indian Journal of Pharmacology” This study found that the methanolic extract of Carthamus caeruleus roots significantly reduced inflammation, promoted wound healing, and enhanced hair growth in experimental models, supporting its traditional use in Northern Algeria as a skincare remedy.
287 citations
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March 1999 in “The Plant Journal” This study found that disrupting the microtubule cytoskeleton in Arabidopsis root hairs caused loss of growth directionality and suggested microtubules interact with calcium gradients to regulate apical growth stability.
May 2022 in “Journal of clinical and nursing research” This review article found that fire needle acupuncture has shown promise in treating alopecia areata by acting directly on skin lesions and regulating Qi and blood, aiming to offer diagnostic and treatment insights for managing the condition.
1 citations
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December 2018 in “International Journal of Current Microbiology and Applied Sciences” This review discusses the traditional uses and pharmacological activities of Citrullus colocynthis, also known as Bitter Apple, but it reports no new clinical results.
October 2025 in “Frontiers in Pharmacology” This review explores the immunopharmacological potential of A. lappa for inflammatory musculoskeletal disorders (IMSDs) but reports no new clinical results, emphasizing the need for standardized research methodologies.
February 2019 in “Mintage journal of pharmaceutical and medical sciences” This article reviews the phytochemical and pharmacological properties of Erythrina variegata but reports that effective anti-alopecia compounds have not yet been identified, suggesting further research is needed.
June 2026 in “ACS Applied Materials & Interfaces” In this study, carbon dots derived from dandelion herb demonstrated significant antibacterial and biofilm-disrupting capabilities, promoting wound healing in a mouse model infected with S. aureus, while also showing excellent biocompatibility and the ability to modulate reactive oxygen species.
201 citations
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August 2006 in “Cell and Tissue Research”
March 2026 in “Critical Care Medicine” In this case study, treatment with methylene blue successfully improved blood pressure in a patient with refractory vasodilatory shock due to massive minoxidil ingestion, highlighting its potential as an adjunctive therapy.