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The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Scarring alopecias are complex hair loss disorders that require early treatment to prevent permanent hair loss.

A patient with a larger than usual genetic mutation had a broader range of symptoms for a muscle disease.

Researchers found genetic mutations causing hypohidrotic ectodermal dysplasia in 88% of studied patients and identified new mutations and genetic variations affecting the disease.

Testing for CAG repeat polymorphism in the androgen receptor gene is not currently recommended for managing hypogonadism.

Some diseases can improve the outcomes of other diseases, leading to new treatment possibilities.

Over half of the children had abnormal hair under a microscope, with many having genetic hair conditions.

The EDAR gene mutation leads to thinner and more deformed hair shafts.

Scientists now better understand the genetics of hypohidrotic ectodermal dysplasia, leading to more accurate diagnoses and potential new treatments.

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

Rabbits lacking the Hoxc13 gene show similar hair and skin issues to humans with ECTD-9, making them good for research on this condition.

The lotion and shampoo effectively treated scalp seborrheic dermatitis.

Fish oil improves skin health in people with diabetes and high cholesterol.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Hair, teeth, and mammary glands develop similarly at first but use different genes later.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

The document concludes that accurate diagnosis of different types of hair loss requires careful examination of hair and scalp tissue, considering both clinical and microscopic features.

Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.

Using CRISPR for gene editing in the body is promising but needs better delivery methods to be more efficient and specific.

Mutations in the LSS gene cause a rare type of hereditary hair loss.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

Short anagen syndrome involves a hair growth phase lasting 1.5 years.

Hair disorders are caused by a complex mix of biology, genetics, hormones, and environmental factors, affecting hair growth and leading to conditions like alopecia.

Eyebrow loss has many causes and requires accurate diagnosis for proper treatment.

Mutations in the HEPHL1 gene cause abnormal hair and cognitive issues.

The research suggests that autophagy-related genes might play a role in causing alopecia areata.