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Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Isotretinoin is highly effective in treating severe acne, rosacea, and gram-negative folliculitis.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.

Current treatments for alopecia show no significant long-term benefits.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.

Pregnancy can cause skin darkening, varicose veins, more sweating, hair growth, hair loss after birth, nail changes, and gum inflammation.

Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

Flutamide effectively reduced excessive hair growth and improved related symptoms in hirsutism patients without significant side effects.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

No single treatment is consistently effective for alopecia areata, and more research is needed.

Psoriasis skin changes are complex and might need several biopsies for a clear diagnosis.

Fullerenes show potential in skin care but need more safety research.

Eating the right nutrients can improve hair health, but taking extra supplements usually doesn't help unless you have a deficiency.

There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.

The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.

Nutraceuticals may improve skin health and protect against aging, but more research is needed on their optimal use and possible health risks.

Treatments for permanent hair loss from scarring aim to stop further loss, not regrow hair, and vary by condition, with partial success common.

The conclusion is that early diagnosis and a multi-system treatment approach are crucial for managing PCOS and its associated health risks.

Trichoscopy helps diagnose and monitor alopecia areata by looking at a combination of specific hair and scalp features.

Skin changes can help diagnose and manage endocrine disorders like thyroid problems, diabetes, and adrenal gland conditions.

Nanoparticle systems make cancer treatment less toxic.

Correcting nutrient deficiencies may help with hair loss, but the benefits of supplements without a deficiency are uncertain and could be harmful.

Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.

Environmental factors, hormones, nutrition, and stress all significantly affect skin health and aging.

Costunolide may have multiple health benefits, including promoting hair growth and protecting against cancer and diabetes, but more research is needed.

Some treatments, like corticosteroids and sensitizing agents, can help with alopecia areata, but more high-quality research is needed.