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21-hydroxylase deficiency causes hormone imbalances leading to various symptoms, and diagnosis involves clinical and genetic tests.

Leydig cell tumors can cause high testosterone and symptoms like hair loss in postmenopausal women, but surgery can improve these symptoms.

Surgical removal of a rare ovarian tumor improved symptoms and hormone levels in a postmenopausal woman.

A woman's rare benign tumor that released both cortisol and testosterone was successfully removed, improving her health.

A thorough diagnostic process and teamwork are crucial for managing complex hyperandrogenism in postmenopausal women.

A 24-year-old woman had a rare ovarian tumor that caused male-pattern hair growth and was hard to diagnose and treat.

A young woman had a rare, aggressive ovarian tumor that was hard to diagnose and treat, leading to disease progression despite treatment.

A rare ovarian tumor was diagnosed in a woman from North Brazil, and surgery is the preferred treatment.

Treating classic 21-hydroxylase deficiency requires precise glucocorticoid dosing and attention to individual patient needs, with new treatments showing promise.

A 20-year-old woman was found to have a rare ovarian tumor causing symptoms like acne and a low-pitched voice, which disappeared after the tumor was removed.

Long-term use of androgens can help manage Hereditary Angioedema (HAE) but may cause serious side effects, so alternative treatments with fewer side effects are being considered.

A 13-year-old girl's masculine symptoms improved after surgery for a rare adrenal tumor that produced male hormones.

A woman's small ovarian tumor causing high androgen levels was missed by several scans but found during surgery.

A woman's rare ovarian tumor was treated with surgery, which stopped her symptoms and normalized her hormone levels.

Rare ovarian tumors can cause increased male hormones in postmenopausal women; surgery is an effective treatment.

A woman's severe hirsutism was caused by Leydig cell tumors in her ovaries, which improved after surgery.

The study found that imaging might miss small ovarian tumors causing high testosterone, and suggested using certain testosterone levels and treatment responses to identify these tumors.

5α-reductase-2 deficiency causes ambiguous genitalia at birth and affects male sexual development, but individuals often develop male characteristics at puberty.

A toddler with a rare adrenal gland tumor causing male-like physical changes was successfully treated with surgery.

Metformin can help diagnose and treat high testosterone levels in women, often due to insulin resistance rather than a tumor.

Hormonal imbalances can cause skin and hair problems in women, and treatments that block male hormones can help.

Hirsutism is excessive male-pattern hair growth in women, often treated cosmetically or with hormone therapy if contraception is also desired.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

With careful management, people with congenital adrenal hyperplasia can have successful pregnancies and become parents.

More research is needed to understand how testosterone is maintained in adult males.

Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.

Treatment with a hormone agonist can reduce excess male hormones in postmenopausal women without surgery.

A woman with high testosterone and an adrenal nodule had an ovarian tumor causing her symptoms, which improved after the tumor was removed.

Insufficient androgen action in male fetuses can cause genital development issues due to genetic mutations or environmental chemicals.

Removing a testosterone-producing tumor cured a woman's sleep apnea and other symptoms.