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Human skin can make serotonin and melatonin, which help protect and maintain it.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

Wnt1/βcatenin signaling is crucial for heart repair after injury.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

PrEP for HIV is less effective in transgender women mainly due to low adherence to the treatment.

Stem cell niches are crucial for regulating stem cell renewal and differentiation, and understanding them can help in developing regenerative therapies.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Some medicinal plants can help heal wounds and may lead to new treatments.

Fibromodulin might help reduce scarring if increased in adult wounds like in fetal skin that heals without scars.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Certain inhibitors slow down plant growth by causing early cell specialization without changing the cell development pattern.

The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.

Alopecia areata causes hair loss, has no cure, and various treatments exist.

Estrogen therapy can reduce skin aging but has cancer risks.

Keratinocytes help heal skin wounds by interacting with immune cells and producing substances that kill pathogens.

The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.

Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.

Male pattern hair loss could hint at androgens affecting COVID-19 severity.

Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.