research Metformin in Dermatology: An Overview
Metformin is effective for various skin disorders but may cause skin side effects.
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research Cutaneous Necrosis After Injection of Polyethylene Glycol–Modified Interferon Alfa
Some patients receiving pegylated interferon alfa injections developed skin necrosis, requiring treatment adjustments or discontinuation.
research Characterization of Novel TMEM173 Mutation with Additive IFIH1 Risk Allele
A new mutation in the TMEM173 gene and a risk allele in IFIH1 cause a unique set of immune-related symptoms.
research PC038: A Rare Case of Strawberry Gingivitis Associated with Granulomatosis with Polyangiitis (Wegener Granulomatosis)
A patient with "strawberry gingivitis" improved after correct treatment for Granulomatosis with polyangiitis, highlighting the need for early diagnosis.
research Analysis of Pediatric Dermatology Inpatient Consultations in a Pediatric Teaching Hospital
Most hospitalized children with skin issues were boys, with allergic skin diseases like atopic dermatitis being most common, and treatments were usually topical.
research Systemic Diseases Associated with Primary Biliary Cirrhosis: A Report of 10 Cases
Early detection and treatment of primary biliary cirrhosis and related autoimmune diseases improve outcomes.
research Genital Dermatology
Different skin conditions show distinct types of vessel inflammation, a new quality of life index for vulval disease is reliable, a certain intrauterine system might be linked to chronic vaginal yeast infections, and oral minoxidil reduces hair loss in women.
research Non-Hemorrhage-Related Adverse Effects of Rivaroxaban
Rivaroxaban can cause liver injury, allergic reactions, blood vessel inflammation, and hair loss, but these side effects are rare.
research Cutaneous Polyarteritis Nodosa Presenting With Digital Gangrene And Breast Ulcer
A young woman with severe symptoms of CPAN improved with intensive treatment but needed a leg amputation.
research A Rapidly Progressive Case of Skin and Soft Tissues Necrosis in a COVID-19 Positive Patient
COVID-19 may lead to severe skin necrosis without clear underlying causes, as seen in a diabetic patient who required leg amputation.
research New England Dermatological Society Meeting on October 1, 1961
Reassurance is important for postpartum hair shedding as it likely won't cause complete baldness.
research Neuropsychiatric Systemic Lupus Erythematosus Presenting as Bipolar I Disorder With Catatonic Features
A girl initially thought to have a psychiatric disorder was later found to have a lupus-related condition, which improved with proper treatment.
research Acute Bullous Dermatosis and Onycholysis Due to High-Dose Methotrexate and Leucovorin Calcium
High-dose methotrexate can cause severe skin and nail issues.
research Case Report: Extensive digital gangrene as a primary manifestation of late-onset systemic lupus erythematosus
A 56-year-old man with no prior history of conditions typically associated with digital gangrene presented with systemic lupus erythematosus (SLE) and digital gangrene as one of the initial symptoms. He exhibited joint pain, hair loss, photosensitivity, mouth ulcers, malar rash, dyspnea, and digital pain. Laboratory tests showed lymphocytopenia and elevated C-reactive protein, with positive antinuclear antibodies. Despite initial treatment with hydroxychloroquine, methylprednisolone, cyclophosphamide, and calcium blockers, the lesions did not improve. However, after two infusions of rituximab, there was a significant improvement in vasculitis lesions and partial improvement in dyspnea. This case highlights digital gangrene as a rare primary manifestation of late-onset SLE.
research 69-Year-Old Man With Nasal Congestion and Pre-Syncope
A 69-year-old man with sinus infection and fainting spells was diagnosed with a rare kidney disease, treated with steroids and a specific drug, which improved his condition.
research Nonpruritic urticaria – a sign of serious systemic disease
A 51-year-old woman developed a nonpruritic urticated rash following a COVID-19 infection, which led to a diagnosis of systemic lupus erythematosus (SLE) with associated symptoms including pericarditis, hypertension, and renal impairment. Histopathology and serology indicated possible neutrophilic urticarial dermatosis (NUD) or hypocomplementemic urticarial vasculitis syndrome (HUVS). The patient later experienced central nervous system vasculitis, treated successfully with methylprednisolone, intravenous immunoglobulin, and plasma exchange. This case underscores the importance of considering serious systemic diseases in patients with nonpruritic urticated rashes and highlights the need for comprehensive serological testing and biopsy for accurate diagnosis and early treatment.
research Case Report: Extensive digital gangrene as a primary manifestation of late-onset systemic lupus erythematosus
A 56-year-old man with no prior risk factors presented with systemic lupus erythematosus (SLE) and digital gangrene as initial symptoms. He exhibited joint pain, hair loss, photosensitivity, mouth ulcers, malar rash, dyspnea, and digital pain. Laboratory tests showed lymphocytopenia and elevated C-reactive protein, with positive antinuclear antibodies. Pulmonary tests indicated fibrosis and restrictive disease. Despite initial treatment with hydroxychloroquine, methylprednisolone, cyclophosphamide, and calcium blockers, the lesions persisted. Rituximab infusions led to significant improvement in vasculitis lesions and partial relief of dyspnea. This case highlights digital gangrene as a rare primary manifestation of late-onset SLE.
research Accelerated UIP: A Special Challenge
Diagnosing and treating rapidly worsening lung disease is difficult and requires better guidelines and understanding.
research Contents
The document discusses how to identify and manage common skin conditions in children.
research Principles of Therapy of Skin Diseases
Use the least toxic, most specific treatments for skin diseases, considering side effects and individual patient needs.
research Cutaneous Drug Reaction Case Reports
Various drugs caused different skin reactions, including allergic and inflammatory responses.
research Dermatologic Therapy: December 1987 to December 1988
New skin treatments in 1987-1988 showed effectiveness for various conditions, but some had side effects or risks.
research Dermatologic Therapy: December 1986 to December 1987
Various dermatologic treatments were effective for skin conditions like acne, rosacea, hair loss, and psoriasis from December 1986 to December 1987.
research Pinnal Diseases in Dogs and Cats
The document concludes that accurate diagnosis is crucial for effectively treating various ear diseases in dogs and cats.
research Dermoscopy of Discoid Lupus Erythematosus: Report of Two Cases
Dermoscopy helped diagnose discoid lupus erythematosus in two patients without needing skin biopsies.
research Effect of Wigs on Perceived Quality of Life in Androgenetic Alopecia Patients
Wigs greatly improve life quality for hair loss patients.
research Drug News
Actemra is approved for a specific artery condition, HIV treatment adherence has improved, women may pay more for a hair loss product, and incorrect dosing of blood thinners can be risky.
research Adverse Cutaneous Reactions to Antipsychotics
Some patients taking antipsychotic medications experience skin reactions, ranging from mild to severe.
research Adverse Cutaneous Reactions to Antidepressants
Skin reactions to antidepressants are common but usually not serious and can be treated.
research Straight Hair Associated with Interferon-Alpha Plus Ribavirin in Hepatitis C Infection
ALA-PDT is effective and safe for chronic X-ray dermatitis, providing complete or partial remission.