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This study found that menopausal status and hormone therapy significantly affect the histology and gene expression of the introitus, with post-menopausal women showing notable tissue remodeling associated with vaginal atrophy.

This meta-analysis found that in postmenopausal women with a history of breast cancer, 8 weeks of vaginal estrogen therapy while on aromatase inhibitors did not result in systemic absorption of sex hormones, suggesting potential safety for treating vulvovaginal atrophy in this context.

This article discusses the use of platelet-rich plasma in genital rejuvenation and reports no new clinical results, suggesting further research is needed to evaluate its effectiveness in this area.

This study concluded that cyproterone acetate alone produced antiandrogenic effects on the female gerbil prostate, while ethinyloestradiol alone stimulated estrogenic activity, and their combination led to prostatic lesions.

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This study assessed clinical patterns of skin and mucosal symptoms in postmenopausal women, finding that a significant number experienced conditions like atrophic vaginitis, oral complaints, and hair loss, often without realizing their menopausal link.

This case report describes a 68-year-old woman with benign mucous membrane pemphigoid and unusual keratotic plaques on her extremities, associated with longstanding mouth and eye symptoms and phalangeal swelling.

This review summarizes characteristics of vaginal moisturizers, lubricants, and washes for managing genitourinary syndrome of menopause, and clarifies common misconceptions about their chemical additives, without providing new clinical results.

This study concluded that both vaginal TEST and Estring may be effective for treating vaginal dryness in breast cancer patients on aromatase inhibitors, with adverse events being rare and manageable.

This review describes the surgical and nonsurgical genital rejuvenation options for addressing hair, morphology, and vascular changes, noting increased interest but providing no new clinical findings.

This systematic review found that estrogen deficiency in postmenopausal women leads to structural and symptomatic changes in genital and cutaneous tissues, with local estrogen therapy providing short-term benefits, while evidence for device-based treatments remains limited and requires larger trials.

The researchers reported that low-dose methotrexate, in combination with surgical dilatation and local treatments, may improve symptoms in patients with severe stenosing vulvovaginal lichen planus.

This study found that CI-1033 caused skin lesions in rats that resemble effects seen in humans receiving EGF receptor inhibitors, suggesting this animal model can help explore the mechanisms behind this cutaneous toxicity.

This study found that intravaginal testosterone significantly improved sexual satisfaction and reduced dyspareunia in postmenopausal women using aromatase inhibitors, with no effect on urinary incontinence.

This study found that overexpression of the mineralocorticoid receptor in a mouse model led to premature epidermal barrier development, keratinocyte apoptosis, and postnatal alopecia, indicating new roles for MR signaling in skin physiology.

This study evaluated 23 cases of MRKH syndrome undergoing neo-vaginal reconstruction using islanded pudendal thigh flaps, finding a 100% flap survival and patency rate, along with satisfactory functional and aesthetic outcomes despite minor issues like hair growth in some patients.

This review highlights the efficacy of transdermal testosterone therapy in improving sexual function in women with hypoactive sexual desire disorder, though approved formulations and long-term safety data are limited.

This article reviews how various hormones may affect female sexual function and provides recommendations for diagnosing and treating endocrinologic sexual difficulties, but it reports no new clinical results.

Menopause often leads to lower sexual desire and discomfort during sex, but treatment should be personalized and only if it bothers the woman.

This review discusses treatments for female sexual dysfunction in postmenopausal women, noting that the effectiveness of current pharmaceutical options is inconclusive and emphasizing the importance of individualized care.

This review examines hair and skin disorders in post-menopausal women and notes a lack of evidence supporting specific treatments for this population.

This study found that telomere shortening disrupts BMP/pSmad/P63 signaling, leading to skin atrophy via Follistatin up-regulation, and suggests potential therapeutic targets.

This study suggests that spironolactone may cause hormonally associated vestibulodynia and female sexual arousal disorder, with symptoms improving after discontinuation and use of a topical estrogen/testosterone gel.

This study found that an imbalance of selenium in a C57BL/6 mouse model led to hair loss with color change and was linked with changes in hair follicle apoptosis markers.

This review discusses the safety of dermatological medications used during pregnancy, highlighting that retinoids have strong teratogenic risks and should be used with caution; it reports no new clinical results.

This report describes a case of Goltz syndrome in a 12-year-old Saudi girl, highlighting the variability in symptoms and the importance of documenting such rare syndromes.

Hormonal contraceptives are effective for teens but require careful consideration of side effects and individual health.

This study describes a method to estimate endogenous hormone production by neutralizing an endogenous hormone with an oppositely acting hormone.

This review discusses lesser-known concerns in transgender dermatology, including neovaginal issues, neoplastic and autoimmune conditions, and the effects of unapproved injectable substances, but reports no new clinical findings.

The document concludes that individualized treatment and lifestyle changes are important for managing menopause symptoms and health risks.