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Natural small molecules can help treat diseases by activating or inhibiting the Wnt pathway.

Wool follicles are complex, involving interactions between different cell types and structures.

COVID-19 patients often have skin issues like chilblain-like lesions and rashes, which can help in early diagnosis and sometimes indicate severe illness.

A man with painful ear plaques was diagnosed with discoid lupus and treated with medications and lifestyle changes.

Scalp biopsies from dermatomyositis patients show chronic hair loss without scarring, with mucin and blood vessel changes being very common.

Avoiding allergens can improve skin and hair conditions in adults with allergic reactions.

Methotrexate caused a rare skin rash in a rheumatoid arthritis patient, which resolved after stopping the drug.

The VVG stain effectively differentiates scar tissue from normal skin and helps classify types of permanent alopecia.

A woman with systemic sclerosis developed a unique scarring hair loss combining features of systemic sclerosis and frontal fibrosing alopecia.

Correct skin biopsy techniques are crucial to avoid misdiagnosis of skin diseases.

Anti-TNF therapy can cause a unique type of hair loss that may get better with topical treatments without stopping the therapy.

The document concludes that early diagnosis and treatment are crucial for children with hair loss to prevent permanent damage, although not all conditions can be effectively treated.

Permanent hair loss from cicatricial alopecia is treated by reducing inflammation and managing symptoms, but regrowth in scarred areas is unlikely.

Transverse scalp sections are better for diagnosing non-scarring hair loss, while vertical sections are better for a specific scarring hair loss called lichen planopilaris.

EVG staining is the most reliable method for diagnosing alopecia.

Biologic treatments for Crohn's disease and ulcerative colitis can cause skin problems, and doctors should adjust treatment if these occur.

The document concludes that new methods improve the accuracy of diagnosing scalp alopecia and challenges the old way of classifying it.

Women with lichen planopilaris often have thyroid disease, depression, anxiety, and may respond to treatment with slowed disease progression.

A mother and daughter with similar hair loss conditions and identical HLA types suggest a genetic link between the conditions.

Skin problems are common after stem cell transplants, and early treatment by dermatologists can improve patient outcomes.

Transverse scalp biopsies are more accurate for diagnosing non-cicatricial alopecia, but examining both types is best for accuracy.

A man got a rare rash from the drug topiramate, which went away after he stopped taking it.

Thymoma in cats can cause hair loss without inflammation.

The document concludes that early diagnosis and treatment are crucial for managing rare hair loss disorders and that more research is needed to improve treatment strategies.

Frontal Fibrosing Alopecia mainly affects postmenopausal Mexican women, requiring early detection to prevent permanent hair loss.

Folliculotropic mycosis fungoides has a worse prognosis than other types, with survival rates varying significantly based on subtype and organ involvement.

Frontal fibrosing alopecia can affect men's beards and leads to permanent hair loss.

A man with HIV had an unusual syphilis rash that looked like folliculitis but was cured with penicillin.

Tofacitinib successfully treated a woman's severe symptoms from a rare autoimmune condition.

A Japanese man with rare skin conditions improved with hydroxychloroquine treatment.