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Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

High levels of TNF-α may contribute to obesity and insulin resistance in PCOS, but not due to the C850T genetic variation.

The document concludes that proper diagnosis and combined treatments are key for hirsutism management, and weight loss may help overweight patients.

Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.

R-spondins and their receptors help increase bone growth and may be used to treat bone loss diseases.

Researchers created a mouse model of a type of rickets that does not cause hair loss.

Potassium channel openers show promise for treating heart disease and other conditions, but more research is needed to fully understand their effects and safety.

The study found that women with hyperandrogenic PCOS have higher levels of AKT1 and AKT2 proteins in their cells, which may lead to cell dysfunction.

Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.

Women with PCOS have more emotional and body image issues than healthy women.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.

Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.

The document concludes that various drugs can manage symptoms and metabolic issues in women with PCOS.

Sexual orientation does not affect the prevalence of PCOS or fertility rates in women undergoing artificial donor insemination.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Adrenal gland disease is common in ferrets and causes hair loss and other symptoms.

Androgen excess disorders in women were effectively treated with spironolactone, estrogen, and dexamethasone.

Losing 5-10% body weight can improve PCOS symptoms, letrozole is better than clomiphene for fertility, and managing weight and blood sugar is important to reduce pregnancy complications.

Metformin helps regulate menstrual cycles, induce ovulation, and improve pregnancy outcomes in women with PCOS.

The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.

New treatments for prostate cancer are less toxic and show promise, but more research is needed to enhance their effectiveness and reduce side effects.

The document concludes that low-dose oral contraceptives and hormonal therapies can manage perimenopause symptoms and reduce some health risks, but lifestyle changes and disease screening are also important.

Women with Polycystic Ovary Syndrome (PCOS) have a lower health-related quality of life, especially those with an anovulatory phenotype, and may need specific interventions to improve it.

Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.

Different diagnostic criteria greatly affect PCOS diagnosis rates in teenagers.

Measuring the distance from the anus to the clitoris may moderately help diagnose polycystic ovary syndrome, especially in certain cases.

The document concludes that various cosmetic and drug treatments are available for hirsutism, and some new drugs show promise.