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Isotretinoin effectively treats severe acne and similar conditions, but has common, mostly reversible side effects, requiring careful patient monitoring.

Finasteride effectively treats baldness but may cause sexual side effects.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Particles around 100 nm can penetrate and stay in hair follicles without passing through healthy skin, making them safe for use in topical products and useful for targeted drug delivery.

No single treatment is consistently effective for alopecia areata, and more research is needed.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Potassium channel openers are effective in treating heart conditions, high blood pressure, pulmonary diseases, bladder issues, and hair loss, but more selective drugs are needed.

Trilostane effectively and safely treats dogs with pituitary-dependent hyperadrenocorticism, improving symptoms and adrenal gland size.

Eflornithine cream effectively reduces women's unwanted facial hair but hair returns if treatment stops.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Finasteride lowers risk of urinary issues and surgery by over 50% in 4 years.

Finasteride improves chronic pelvic pain, saw palmetto doesn't.

Minoxidil helps hair growth in 63.6% of alopecia patients, with 27.3% having excellent results.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

Thymus transplantation successfully restored immune function in infants with FOXN1 deficiency.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

Voriconazole can cause serious side effects, especially in long-term use.

Finasteride effectively treats hidradenitis suppurativa for most patients.

A very low-calorie ketogenic diet is effective for quick weight loss and improving health in obese patients, with careful management of side effects and maintenance.

Minoxidil effectively treats severe hypertension but may cause side effects, so careful monitoring is needed.

Spironolactone most effective for hirsutism, but has side effects.

The conclusion is that early diagnosis and a multi-system treatment approach are crucial for managing PCOS and its associated health risks.

Finasteride may reduce prostate bleeding by lowering blood vessel growth factor levels and blood vessel density in certain prostate areas.

Taking 1 mg/day finasteride for hair loss significantly lowers PSA levels in men, which may affect prostate cancer screening.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.

Targeted cancer therapies often cause skin reactions, so dermatologists must manage these effects.

The document concludes that specific itchy skin diseases during pregnancy have varying fetal risks and treatments, including corticosteroids and other medications.

Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.