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Genetic defects in the glucocorticoid receptor gene can cause conditions with abnormal sensitivity to stress hormones, and other factors may also affect this sensitivity.

Mutations in the NR3C1 gene cause a rare condition that affects hormone signaling and can lead to various symptoms, with dexamethasone as a treatment option.

PCOS is a condition causing irregular periods, excess male hormones, and infertility, often managed by targeting insulin resistance and specific symptoms.

Skin lesions in Carney Complex are caused by a gene change in some skin cells that leads to increased pigmentation and may lead to tumors.

The document concluded that more research is needed to understand how estrogen affects the enzyme involved in hirsutism development.

The document concludes that inflammation markers can be used in diabetes, vitamin D3 affects immune pathways, hyperthyroidism changes hormone levels, androgen levels help diagnose Adrenocortical Carcinoma, erectile dysfunction is linked to diabetes, hypogonadism is common in HIV-infected males, and hormones can be biomarkers for various conditions.

Postmenopausal hyperandrogenism, a condition with symptoms like increased hair growth and acne, is usually caused by PCOS but can also be due to other factors. It's diagnosed by checking testosterone levels and treated either by removing the adrenal tumor or through antiandrogen therapy.

A woman with childhood growth hormone deficiency had multiple hormone deficiencies and developed serious lung and kidney problems later in life.

A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.

Androgens significantly affect female hair loss, and hormonal treatments may help.

High androgen levels can cause excessive hair growth and may indicate serious health issues, including heart disease and fertility problems.

Rare adrenal cancers that secrete androgens or estrogens have a poor prognosis and are treated primarily with surgery.

Bariatric surgery patients need careful before and after surgery care for safety and long-term health.

Reduced androgens linked to kinky hair disorder and hair loss; 5a-reductase inhibitors may help.

Pioglitazone improved insulin sensitivity and altered cortisol metabolism in PCOS patients.

High levels of cortisol in hair show long-term stress which can lower fertility in animals.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

A Shi Tzu dog with high cortisol levels improved after increasing the dose of trilostane.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

Moving horses to new places can increase their stress levels, as shown by higher stress hormone in their hair.

Shift nurses show altered body temperature and stress hormone levels, suggesting their body clocks adjust to irregular schedules.

The cause of atypical Cushing's syndrome in dogs, possibly linked to sex hormones, is not yet proven.

Hyperadrenocorticism in ferrets is linked to neutering and indoor housing, and is best treated with surgery and a deslorelin implant.

Hirsutism is common body hair growth due to genetics and hormones, and while not a disease, it can be distressing; virilisation includes hirsutism with other male traits and needs medical attention.

A postmenopausal woman's virilization was caused by a rare ovarian tumor that was hard to detect but was successfully treated with surgery.

Doctors need to be better prepared to assess and treat obesity in patients.

Effective hirsutism management requires identifying the cause, combining new and traditional treatments, and setting realistic expectations for patients.

PCOS is a common hormonal disorder with symptoms like irregular periods and excess hair growth, managed with lifestyle changes and medications.

The conclusion is that obesity should be managed with a slow, balanced approach to diet and exercise, with medication and surgery as additional options, and education and access to care are important.

Hair cortisol is a reliable marker of long-term cortisol levels and is linked to daytime saliva cortisol but not morning levels.