research 5α-Reductase Inhibitors
Finasteride effectively treats enlarged prostate and male baldness, improves symptoms of hirsutism in women, but doesn't work for acne, and may delay prostate cancer progression with few side effects.
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research Therapeutic Effects of Stem Cells in Different Body Systems: A Comprehensive Review
Stem cell therapy is promising for treating various health conditions, but more research is needed to understand its full potential and address challenges.
research Cystitis Due to Cytoxan: Case Report
A woman developed severe bladder inflammation after cancer treatment with Cytoxan.
research Molecular, immunological, enzymatic and biochemical studies of coproporphyrinogen oxidase deficiency in a family with hereditary coproporphyria.
The study focused on a 27-year-old woman with hereditary coproporphyria, characterized by recurrent renal pain, dark urine, and hair loss, but no photosensitivity. Elevated urinary porphyrin metabolites and fecal studies confirmed the diagnosis, with decreased coproporphyrinogen oxidase activity at 35% of normal levels. Her mother and sisters were identified as heterozygous carriers of the condition, showing reduced enzyme activity up to 50%. A novel mutation was discovered in the coproporphyrinogen oxidase gene, involving a cytosine to thymine transversion at nucleotide position 854. Immunological studies indicated decreased enzyme protein concentrations in the patient and her family members.
research Prostate-Specific Antigen as a Marker of Hyperandrogenism in Women and Its Implications for Antidoping
PSA levels could help detect illegal steroid use in female athletes but face challenges like cost and PCOS prevalence.
research Lack of Endocrine Systemic Side Effects After Topical Application of Spironolactone in Men
Topical spironolactone cream doesn't cause hormone-related side effects in the body.
research Platelet-Rich Plasma: A Promising Regenerative Therapy in Gynecological Disorders
Platelet-rich plasma shows promise for treating various female reproductive health issues but requires more research.
research The Clinical Applications of Five-Alpha Reductase Inhibitors
Five-alpha reductase inhibitors, like finasteride and dutasteride, can treat enlarged prostates, improve urination, reduce need for prostate surgery, and lower the risk of prostate cancer, but may increase the risk of higher grade prostate cancer. They can also treat male pattern baldness.
research Canine Alopecia X-Like Disorder
The dog likely has a condition similar to Canine alopecia X.
research Prevalence of Respiratory Disorders in Patients With Cleft Lip and Palate: Systematic Review
People with cleft lip and palate often have respiratory problems.
research Analysis of Benign Prostatic Obstruction Surgery: A Long-Term Evaluation in a Real-Life Context
Prostate surgery is often effective long-term, but some patients may need more treatment or another surgery, especially if they had prostatitis before.
research 5-Alpha Reductase Inhibitors: New Evidence on Benefits and Harms Beyond Benign Prostatic Hyperplasia
5-alpha reductase inhibitors may have additional effects on cancer, mental health, heart health, and hormone levels beyond treating prostate enlargement.
research Evaluation of Coronary Sinus Strain in Patients with Dipper and Non-Dipper Hypertension
People with non-dipper hypertension have higher aldosterone levels, more strain on their heart's venous system, and increased risk of endothelial dysfunction.
research Clinical Analysis of Systemic Lupus Erythematosus in the Elderly for 33 Cases
Elderly SLE patients show fewer typical symptoms and more hormonal side effects.
research 66-Year-Old Woman With Painless Vesicular Lesions
A woman was diagnosed with porphyria cutanea tarda and improved with phlebotomy and lifestyle changes.
research The Influence of Portocaval Shunting on Inner Ear Structures
PCS rats show significant inner ear damage and zinc deficiency, similar to liver cirrhosis patients.
research Every Transurethral Resection of the Prostate Is Not Just Benign Prostatic Hyperplasia
TURP specimens should be checked for various tumors, not just common prostate issues.
research The Long-Term Effect of Doxazosin, Finasteride, and Combination Therapy on the Clinical Progression of Benign Prostatic Hyperplasia
Combination therapy of doxazosin and finasteride safely and effectively reduces benign prostatic hyperplasia progression risk.
research The Effect of Finasteride in Men with Benign Prostatic Hyperplasia
Finasteride effectively treats BPH but may increase sexual dysfunction risk.
research Use of Cyproterone Acetate in the Treatment of Acne, Hirsutism, and Virilism
Cyproterone acetate is effective for acne but less so for hirsutism and alopecia, with some side effects and quick menstrual cycle recovery after treatment.
research The Clinical Development of a 5α-Reductase Inhibitor, Finasteride
Finasteride effectively treats BPH, but needs more trials to understand potential.
research Dihydrotestosterone and the Concept of 5-Alpha-Reductase Inhibition in Human Benign Prostatic Hyperplasia
Blocking the enzyme that turns testosterone into DHT can safely and effectively treat enlarged prostate.
research Case Series of Selenium Toxicity from a Nutritional Supplement
Excessive selenium from a supplement caused toxicity but patients recovered with care.
research Therapeutic, Prophylactic, and Functional Use of Probiotics: A Current Perspective
Probiotics show promise for health benefits but need more research to understand how they work.
research Epitestosterone: Regulatory Roles in Androgen-Dependent Processes
Epitestosterone may counteract testosterone's effects and has roles in body processes like prostate growth and hair distribution.
research Edible Seeds From Cucurbitaceae Family as Potential Functional Foods: Immense Promises, Few Concerns
Edible seeds from the Cucurbitaceae family like pumpkin and watermelon seeds are nutritious and may have health benefits, but eating too much can cause side effects.
research Inhibitors of 5α-Reductase in the Treatment of Benign Prostatic Hyperplasia
5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.
research Environmental Stress But Not Subjective Distress in Children or Adolescents With Alopecia Areata
Kids with alopecia areata may experience more stress but not necessarily feel more anxious or depressed than others.
research Biotin Deficiency in an Infant Fed with Amino Acid Formula
Biotin supplements improved skin and hair in a biotin-deficient infant on amino acid formula.
research 5-Alpha Reductase Deficiency
5-alpha reductase deficiency leads to male sexual development issues and treatments like finasteride help with prostate enlargement and hair loss.