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    Glossary Type I Collagen

    most abundant protein in skin, bones, and tendons

    Type I Collagen is the most abundant collagen in the human body, making up about 90% of the collagen found in skin, bones, tendons, and other connective tissues. It provides structural support and strength, playing a crucial role in wound healing and maintaining the integrity of various tissues.

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    1. Type XVII collagen coordinates proliferation in the interfollicular epidermis eLife · 2017 · 124 citations
    2. Changes in fibronectin, laminin and type IV collagen distribution relate to basement membrane restructuring during the rat vibrissa follicle hair growth cycle. PubMed · 1992 · 45 citations
    3. Basement Membrane Zone Remodeling During Appendageal Development in Human Fetal Skin. The Absence of Type VII Collagen is Associated with Gelatinase-A (MMP2) Activity Journal of Investigative Dermatology · 2000 · 42 citations
    4. The distributions of type IV collagen .ALPHA. chains in basement membranes of human epidermis and skin appendages Archives of Histology and Cytology · 2007 · 36 citations
    5. Long-Term Survival of Type XVII Collagen Revertant Cells in an Animal Model of Revertant Cell Therapy Journal of Investigative Dermatology · 2013 · 27 citations
    6. Type III Collagen Regulates Matrix Architecture and Mechanosensing during Wound Healing Journal of Investigative Dermatology · 2024 · 24 citations
    7. Characterization of dermal type I collagen of C3H mouse at different stages of the hair cycle British Journal of Dermatology · 1999 · 15 citations
    8. Expression of anti-aging type-XVII collagen (COL17A1/BP180) in hair follicle-associated pluripotent (HAP) stem cells during differentiation Tissue & Cell · 2019 · 11 citations
    9. Expression of laminin, type IV collagen and fibronectin molecules is related to embryonal skin and epidermal appendage morphogenesis. PubMed · 2001 · 10 citations
    10. Promoting effect of type 17 collagen production by chlorogenic acid using PLGA nanoparticles in the human epidermal keratinocyte cell Journal of Drug Delivery Science and Technology · 2020 · 8 citations
    11. Coculture of Human Hair Follicles and Dermal Papillae in Type I Collagen Gel Annals of the New York Academy of Sciences · 1991 · 7 citations
    12. Histological and molecular restoration of type VII collagen in Recessive dystrophic epidermolysis bullosa mouse skin by topical injection of keratinocyte-like cells differentiated from human adipose-derived mesenchymal stromal cells Journal of Dermatological Science · 2024 · 1 citations
    13. Bacitracin-Loaded Type I Collagen/Bacterial Cellulose Dressing for the Repair of Infected Wounds Journal of Functional Biomaterials · 2026
    14. Mesenchymal stem cell-derived exosomes promote scalp rejuvenation through type XVII collagen regulation via the miR-21-5p/DKK2/Wnt pathway Frontiers in Cell and Developmental Biology · 2026
    15. Recombinant Type XVII Collagen Promotes Hair Growth by Activating the Wnt/β-Catenin and SHH/GLI Signaling Pathways Cosmetics · 2025
    16. Silk fibroin hydrogel with recombinant silk fibroin/NT3 protein enhances wound healing by promoting Type III collagen synthesis and hair follicle regeneration in skin injury Materials Today Bio · 2025
    17. Synergistic Effects of Fractional CO <sub>2</sub> Laser and Recombinant Humanized Type III Collagen (rhCol III) in Atrophic Acne Scar Treatment: Activation of MAPK Pathway and Enhanced Collagen Remodeling Dermatologic Therapy · 2025
    18. Identification of a human type XVII collagen fragment with high capacity for maintaining skin health Synthetic and systems biotechnology · 2024
    19. 583 Induction of type 17 collagen decreases ultraviolet b-induced cellular senescence in human htert/ker-ct keratinocytes 2022
    20. Type XVII collagen suppresses interfollicular epidermal proliferation in neonatal and aged skin, and helps rejuvenate epidermis 2017
    21. Author response: Type XVII collagen coordinates proliferation in the interfollicular epidermis 2017
    22. Decision letter: Type XVII collagen coordinates proliferation in the interfollicular epidermis 2017
    23. Distribution of Type XII and XIV Collagens in Bovine Dermis and Hair Follicles Connective tissue · 2001
    24. Alterations of collagen type 1, skin fibroblasts, and macrophages in the scalp following the treatment of 1550‐nm erbium glass fractional laser for androgenetic alopecia Journal of Cosmetic Dermatology · 2021
    25. Inhibitory effect of angiogenin on the expression of type I collagen and fibronectin in dermal papilla cells from androgenetic alopecia areas Chinese Journal of Dermatology · 2018
    26. [Effects of collagen type ⅩⅦ α1 on epidermal stem cells in aging skin and the microRNA intervention mechanism]. PubMed · 2022
    27. Expression of collagen type I, skin fibroblasts and macrophages after 1550 nm erbium glass fractional laser in androgenic alopecia 2020
    28. Biological Macromolecule Hydrogel Based on Recombinant Type I Collagen/Chitosan Scaffold to Accelerate Full-Thickness Healing of Skin Wounds Polymers · 2023 · 12 citations
    29. Plasma-Polymerised Antibacterial Coating of Ovine Tendon Collagen Type I (OTC) Crosslinked with Genipin (GNP) and Dehydrothermal-Crosslinked (DHT) as a Cutaneous Substitute for Wound Healing Materials · 2023 · 6 citations
    30. DAB-labelling for collagen type III and PDGFR as control on equine skin sections. OPAL (Open@LaTrobe) (La Trobe University) · 2025