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The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

Proper control of β-catenin activity is crucial for development and preventing diseases like cancer.

Deleting the Trf1 protein in mice is safe and may help prevent cancer without major side effects.

Male pattern baldness is linked to a higher risk of certain skin cancers, especially on the scalp.

The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Different types of skin cells play specific roles in development, healing, and cancer.

Some herbal therapies may help with skin conditions, but more research is needed to confirm their safety and effectiveness.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Stem cell niches support, regulate, and coordinate stem cell functions.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Fat tissue cells are a promising option for healing various diseases, but more research is needed to ensure they are safe and effective.

The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Transit-amplifying cells are crucial for tissue repair and can contribute to cancer when they malfunction.

Nanomaterials in biomedicine can improve treatments but may have risks like toxicity, needing more safety research.

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.

The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.

Stem cell differentiation is crucial for skin barrier maintenance and its disruption can lead to skin diseases.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

Found microRNA differences in hair cells, suggesting potential treatment targets for hair loss.

New techniques have enhanced our understanding of how stem cells function and the role of mutations in aging tissues, which may influence future cancer therapies.

Eclipta alba extract may work as an anticancer agent and help reverse drug resistance.

Some herbal treatments are effective for skin disorders, but more research and regulation are needed.

Astrotactin proteins are important for brain and skin development and are linked to several neurodevelopmental disorders.

SOX9 helps determine stem cell roles by interacting with DNA and proteins that control gene activity.

STAT3 signaling is important for healthy skin and hair follicles, and its disruption can lead to skin conditions like atopic dermatitis.