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Deleting the MAD2L1 gene in mice led to rapid tumor growth despite chromosomal instability.

SSAT is a key enzyme affecting cell growth and metabolism, with potential but risky use in disease treatment.

Involucrin gene expression is controlled by specific proteins and signaling pathways.

Targeting the Smoothened receptor shows promise for treating certain cancers.

The protein p53 directly reduces the production of Keratin 17, a skin and hair protein, in rats with radiation dermatitis.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Mice without certain skin enzymes have faster hair growth and bigger eye glands.

Certain genetic changes in the LSS gene cause a rare skin and hair condition.

Caspases are enzymes important for both cell death and various non-lethal cell functions, affecting head development and hair growth, with different caspases playing specific roles.

Wnt/β-catenin signaling is important for keeping skin cell attachment structures stable.

The study concludes that regulating apoptosis could lead to new treatments for various skin and hair conditions.

A specific gene variant is linked to heart disease, increased heart muscle, curly hair, and thick skin on palms and soles.

A new syndrome was linked to two new genetic changes in the MBTPS1 gene in a 14-year-old girl.

The G60S Connexin43 mutation causes hair growth issues and poor hair quality in mice, similar to human ODDD patients.

New treatments for advanced skin cancer are improving patient outcomes, but drug resistance and finding the right treatment combinations are still big challenges.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

Pitx2 helps outer root sheath cells differentiate but can't start hair growth on its own.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

ΔNp63α stops TAp73β from working in skin cancer by blocking its access to specific genes, not by directly interacting with it.

The research shows that a gene called Wnt3 affects hair growth and structure, causing short hair and balding when overactive.

Different forms of hair loss drug can improve effectiveness.

Researchers found key regions in the mouse hairless gene that control its activity in skin and brain cells, affecting hair follicle function.

The workshop discussed the role of a protein called calreticulin in health and disease, its potential as a treatment target, and its possible use as a disease marker.

A new genetic change in the keratin 10 gene caused a skin condition called ichthyosis hystrix in a father and his daughter.

Truncating mutations in the C2orf37 gene cause Woodhouse–Sakati syndrome.

A woman with a new PTCH gene mutation has both Gorlin syndrome and severe hair loss.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

Cantú syndrome is caused by mutations in the ABCC9 gene.

The study found two new mutations in a Chinese patient with severe biotinidase deficiency.

Patients with Bohring-Opitz syndrome and ASXL1 mutations need regular kidney ultrasounds to check for tumors.