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    Glossary Trichilemmal Keratinization

    Trichilemmal keratinization is a specific type of keratinization that occurs in the outer root sheath of hair follicles. It is characterized by the formation of a distinct layer of keratin that is more compact and less organized than that found in other types of keratinization, such as that in the epidermis. This process is relevant to hair biology as it plays a role in the structural integrity of hair follicles and can influence hair growth and health. Distinguishing features include the presence of a clear zone of keratinized cells that can be observed histologically, which may be associated with certain hair disorders or conditions affecting hair loss.

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    Research 30 of 232

    1. Outer root sheath keratinization in anagen and catagen of the mammalian hair follicle. A seventh distinct type of keratinization in the hair follicle: trichilemmal keratinization. PubMed · 1981 · 59 citations
    2. Multifocal Malignant Proliferating Trichilemmal Tumour: A Diagnostic Imitator Beyond the Scalp International Journal of Research and Innovation in Applied Science · 2026
    3. Ultrastructural characteristics of trichilemmal cysts: report of two cases Medical Electron Microscopy · 2001 · 2 citations
    4. Baker′s dozen on the scalp: An interesting case of multiple trichilemmal cyst Journal of Cutaneous and Aesthetic Surgery · 2014 · 5 citations
    5. Trichilemmal Carcinoma of the Thigh Dermatology Review · 2025
    6. A Case of Proliferating Trichilemmal Cyst with Trichoepitheliomatous Change Linchuang pifuke zazhi · 2002
    7. Pilomatricoma can differentiate not only towards hair matrix and hair cortex, but also follicular infundibulum, outer root sheath and hair bulge Experimental Dermatology · 2009 · 18 citations
    8. [An immunohistochemical study on cell differentiation in the outer root sheath of the normal human anagen hair follicles with antikeratin monoclonal antibodies]. PubMed · 1990 · 6 citations
    9. Pathologic Quiz Case: A Nodule on the Back Archives of Pathology & Laboratory Medicine · 2000 · 5 citations
    10. A previously undescribed cutaneous paraneoplastic syndrome in a cat with thymoma Veterinary dermatology · 2019 · 2 citations
    11. Follicular Hybrid Cyst With Isthmic-Catagen, Pilomatrical, and Syringocystadenoma Papilliferum Components American Journal of Dermatopathology · 2012 · 2 citations
    12. Trichilemmoma.Features of keratin expression in CS-5 trichocyst system tumors. Skin Cancer · 1995 · 1 citations
    13. Onycholemmal horn: A distinctive subungual tumour Journal of the European Academy of Dermatology and Venereology · 2023
    14. Cycle pilaire et alopécie X chez le chien Pratique médicale & chirurgicale de l'animal de compagnie · 2008
    15. Hair sheath keratins in follicular tumors. (5). Identification of hair sheath keratins in keratoacanthoma; Histopathological hair sheath structures in the tumor and their significance as differential histopathological criteria from squamous cell carcinoma. The Nishinihon Journal of Dermatology · 1990
    16. Trichilemmoma.Cell biology of the normal human outer root sheath. Skin Cancer · 1995
    17. Histopathologic Criteria for Follicular Differentiation 2017 · 1 citations
    18. 1375 Cutaneous adnexal cysts revisited: A novel classification based on morphological and molecular features Journal of Investigative Dermatology · 2018
    19. The Molecular Pathogenesis of Trichilemmal Carcinoma Research Square (Research Square) · 2020
    20. The Molecular Pathogenesis of Trichilemmal Carcinoma Research Square (Research Square) · 2020
    21. Proliferative trichilemmal cyst of the plantar surface: An unusual localization: A case report World Journal of Advanced Research and Reviews · 2026
    22. A Rare Case of Proliferating Trichilemmal Tumor Treated with Radiotherapy Journal of medical science and clinical research · 2024
    23. A Case Report of Kaphaja Granthi w.s.r. to Trichilemmal Cyst Journal of Ayurveda and Integrated Medical Sciences · 2025
    24. Proliferating Trichilemmal Tumor Presenting as a Scrotal Mass in a Middle-Aged Male: An Uncommon Location Clinical Dermatology Open Access Journal · 2017 · 1 citations
    25. Scalp Reconstruction after Resection of a Large Recurred Proliferating Trichilemmal Tumor Using an Anterolateral Thigh Free Flap Archives of Plastic Surgery · 2013 · 6 citations
    26. Expression of the Orphan Protein Plet-1 during Trichilemmal Differentiation of Anagen Hair Follicles 2010 · 30 citations
    27. The molecular pathogenesis of Trichilemmal carcinoma BMC Cancer · 2020 · 19 citations
    28. Trichilemmal cyst of the eyelid: An unusual presentation in paediatric age group Indian Journal of Ophthalmology - Case Reports · 2026
    29. Cutaneous Tumours of Pilar Origin with Associated Syndromes Research Review · 2023
    30. Multicentric calcified trichilemmal cysts with alopecia universalis affecting siblings Indian Journal of Dermatology Venereology and Leprology · 2012 · 9 citations