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New treatments targeting the Hedgehog pathway can help treat advanced skin cancer but may have side effects and their effectiveness in early stages is unknown.

The document concludes that certain mutations may contribute to the inflammation in hidradenitis suppurativa and suggests that targeting TNFα could be a treatment strategy.

Psoriasis worsens in winter in India due to less sunlight and dry skin, needing personalized treatment.

Baricitinib is effective and safe for treating severe alopecia areata.

Finasteride increases hair count and improves hair growth with low risk of side effects.

The hair growth solution reduced hair loss and increased hair thickness in a small group of patients.

TICE salvage chemotherapy is effective for treating germ-cell tumors with poor prognosis.

Female pattern hair loss can be treated with medications, surgery, and cosmetic products, considering its psychological impact.

Pancreatic cancer pain management is inadequate due to the disease's severity and limited effectiveness of treatments.

Etoposide is effective in treating several cancers, especially small cell lung cancer, with acceptable side effects.

Eribulin-based chemotherapy is more effective and has fewer side effects for advanced triple-negative breast cancer.

Metformin improves menstrual cycles and hormone levels in women with PCOS, mostly within the first 6 months.

Hair loss treatments show limited improvement, sunscreen thickness affects vitamin D production, and the effectiveness of IVIg for toxic epidermal necrolysis is uncertain.

Baricitinib improved severe hair loss in adults over 52 weeks and was safe to use.

Afatinib often causes skin problems that need proactive management.

Calcipotriol works almost as well as clobetasol for mild to moderate alopecia areata with fewer side effects.

PRP and cell therapies may help with hair loss, but more research is needed.

5% minoxidil foam is a safe, effective treatment for male pattern hair loss, with increased hair count and few side effects.

Combining pulsed prednisone with tofacitinib can lead to lasting hair regrowth in severe alopecia areata patients.

Leflunomide is effective for rheumatoid arthritis but has significant side effects.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Combining electrodynamic microneedle with 5% minoxidil improves hair growth and reduces hair loss in Chinese men.

New treatments for Alopecia Areata, like JAK inhibitors, show promise for hair regrowth and are likely to change future treatment approaches.

Blocking RANK signaling might help treat metastatic melanoma, but more research is needed.

New therapies for alopecia areata show potential but need more research.

Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.

Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.

Tacrolimus solution is effective and well-tolerated for treating inflammatory scalp conditions.

Metformin has limited effectiveness for improving PCOS symptoms and lacks clear benefits, needing more research to confirm its efficacy.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.