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Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Vitamin D is important for skin health and may affect conditions like psoriasis and hair loss, but more research is needed to understand its role fully.

Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

Stem cell therapy, particularly using certain types of cells, shows promise for treating hair loss by stimulating hair growth and development, but more extensive trials are needed to confirm these findings.

Stem cells in the hair follicle are regulated by their surrounding environment, which is important for hair growth.

Antibiotics can reduce acne but may lead to resistant bacteria, and understanding the skin's bacteria is important for treatment.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Tofacitinib may help treat severe hair loss, but more research is needed.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Gene therapy with the Math1 gene helped regenerate balance-related cells and improve balance in mice.

Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.

Fat cells in the skin help start healing and form important repair cells after injury.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Male pattern baldness involves hormones and cell signals affecting hair growth.

Different PIN proteins affect plant root hair growth by changing how auxin is transported.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Platelet-rich plasma might help with hair growth and skin conditions, but more research is needed to prove its effectiveness and safety.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Rhodococcus equi causes severe pneumonia in young foals, and effective vaccines are needed due to foals' weak immune responses.

The document concludes that while significant progress has been made in understanding skin biology and stem cells, more research is needed to fully understand their interactions with their environment.