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Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.

Human hair follicle organ culture is a useful model for hair research with potential for studying hair biology and testing treatments.

Msx2 and Foxn1 are both crucial for hair growth and health.

Polycomb Repressive Complex 2 is not needed for hair regeneration.

The Hairless gene is crucial for hair cell development, affecting whether skin cells become hair or skin and oil gland cells.

The document concludes that individuals with a rare genetic disorder linked to the AEBP1 gene may experience a unique type of hair loss and should be monitored for heart issues.

Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.

Cells from a skin condition can create new hair follicles and similar growths in mice, and a specific treatment can reduce these effects.

Most dogs have hair whorls on their chest and limbs, with shelter dogs and short-haired dogs having more chest whorls.

Removing the VDR gene in skin cells reduces their growth and affects hair-related genes.

The gene Ascl4 is not necessary for the development of hair, teeth, or mammary glands.

The report concludes that atypical Brauer nevus is more common in males, present at birth, and often misdiagnosed due to its unusual scalp locations.

Ovol2 is crucial for hair growth and skin healing by controlling cell movement and growth.

Caffeine penetrates human skin in lab tests similarly to real-life conditions, but actual skin use is still essential for accurate results.

Topical PUVA and tacrolimus ointment can effectively and safely treat infant alopecia universalis.

Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.

This therapy effectively treats resistant alopecia areata with minimal side effects.

Melanocytes produce melanin; their defects cause vitiligo and hair graying, with treatments available for vitiligo.

A specific immune response helps control mite populations on the skin, maintaining healthy hair follicles.

Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.

Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.

Body hair transplantation is an effective method for restoring hair in people with severe baldness and limited scalp donor hair.

The we/we wal/wal mice have defects in hair growth and skin layer formation, causing hair loss, useful for understanding alopecia.

Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.

University students in Egypt experienced high stress during COVID-19's third wave, with negative coping mechanisms being more common.

A dog's chronic bite wound healed successfully using a mix of herbal gel, low power laser, and ozone therapy.

The document concludes that diagnosing hair loss requires evaluating multiple histological features, as no single feature is definitive on its own.

Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.

Venous catheterization may help diagnose the cause of female hyperandrogenism when imaging is unclear.