A Brief Study on Alopecia Areata

April 2024 in “ International Journal of Research Publication and Reviews ”

Kailash C. Gupta, Vijay Singh, Rohit Singh Padiyar

alopecia areata nonscarring hair loss autoimmune condition topical corticosteroids immunotherapy minoxidil alopecia totalis alopecia universalis Rogaine

TLDR Alopecia areata causes hair loss with varied treatment responses and frequent relapses.

Alopecia areata (AA) is an autoimmune condition causing nonscarring hair loss on the scalp or body, often presenting as sharply demarcated round patches. It can occur at any life stage and is commonly associated with atopy and autoimmune thyroiditis. Treatments, including topical, systemic, and injectable medications, show varied responses and frequent relapses, highlighting an unmet clinical need. The etiology involves genetic and environmental factors, with recent advancements in genetic research. Treatment options include topical corticosteroids, immunotherapy, and minoxidil. AA can also affect nails and may progress to alopecia totalis or alopecia universalis.

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Research cited in this study

13 / 13 results

research Alopecia Areata: An Update on Etiopathogenesis, Diagnosis, and Management

290 citations , August 2021 in “Clinical Reviews in Allergy & Immunology”

JAK inhibitors show promise for treating alopecia areata, but more research is needed.

research Hair Follicle Immune Privilege and Its Collapse in Alopecia Areata

134 citations , July 2020 in “Experimental dermatology”

Hair follicles are normally protected from the immune system, but when this protection fails, it can cause hair loss in alopecia areata.

research Targeting the Janus Kinase Family in Autoimmune Skin Diseases

124 citations , October 2019 in “Frontiers in Immunology”

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

Combination Therapy with Cyclosporine and Psoralen Plus Ultraviolet A in Patients with Severe Alopecia Areata: A Retrospective Study with a Self-Controlled Design

research Combination Therapy with Cyclosporine and Psoralen Plus Ultraviolet A in Patients with Severe Alopecia Areata: A Retrospective Study with a Self-Controlled Design

21 citations , January 2013 in “Annals of dermatology/Annals of Dermatology”

The combination of cyclosporine and PUVA might help treat severe alopecia areata.

research Alopecia Areata: An Update

67 citations , January 2013 in “Indian Journal of Dermatology, Venereology and Leprology”

The document concludes that alopecia areata is an autoimmune disease without a definitive cure, but treatments like corticosteroids are commonly used.

research Congenital Triangular Alopecia: A Close Mimicker of Alopecia Areata

13 citations , January 2011 in “International Journal of Trichology”

CTA is often mistaken for AA but doesn't respond to steroids and may require hair transplantation.

research Coudability Hairs: A Revisited Sign of Alopecia Areata Assessed by Trichoscopy

56 citations , June 2010 in “Clinical and experimental dermatology”

Coudability hairs are useful markers for alopecia areata activity.

research Acute Diffuse And Total Alopecia: A New Subtype Of Alopecia Areata With A Favorable Prognosis

64 citations , November 2008 in “Journal of The American Academy of Dermatology”

A new type of rapid hair loss called ADTA usually gets better on its own within 6 months.

research Clinical Significance of Dermoscopy in Alopecia Areata: Analysis of 300 Cases

196 citations , June 2008 in “International Journal of Dermatology”

Dermoscopy helps diagnose and manage alopecia areata by showing specific hair changes.

research The Role of Scalp Dermoscopy in the Diagnosis of Alopecia Areata Incognita

150 citations , April 2008 in “Journal of The American Academy of Dermatology”

Scalp dermoscopy is good for diagnosing a type of hair loss and helps choose the best spots for biopsy.

research The Pattern and Profile of Alopecia Areata in Singapore: A Study of 219 Asians

275 citations , November 2002 in “International Journal of Dermatology”

Alopecia areata mainly affects young people and has significant psychological impacts, especially in males.

research Onion Juice (Allium cepa L.), A New Topical Treatment for Alopecia Areata

95 citations , June 2002 in “The Journal of Dermatology”

research Juvenile versus maturity-onset alopecia areata- a comparative retrospective clinical study

164 citations , November 1989 in “Clinical and Experimental Dermatology”

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research Twenty Nail Dystrophy with Alopecia Areata in an Atopic Child

April 2019 in “International journal of research in dermatology”

A child with rough nails also had hair loss and allergies.