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This review outlines recent progress in CRISPR/Cas9 genome editing, discussing its structure, mechanisms, and the use of genetic, chemical, and physical strategies to enhance precision and reduce off-target effects despite some persistent challenges for clinical application.

This review discusses various methods for delivering CRISPR/Cas9 for gene editing in vitro and in vivo, highlighting delivery as a major challenge but reports no new experimental results.

This review discusses the cosmetic potential of Southeast Asian herbs and highlights the need for more systematic scientific evaluation of their efficacy and safety.

In this study, ELE was found to protect against oxidative stress-induced testosterone reduction in TM3 Leydig cells by increasing testosterone synthesis and decreasing its conversion.

This study highlights the gap between media claims and limited scientific evidence on the impact of alternative therapies for men's health, emphasizing the need for larger-scale trials for informed patient counseling.

This review examines the pharmacological evidence and bioactive compounds in Hibiscus plants, supporting their potential importance for developing treatments for chronic and degenerative diseases, though more research is needed.

This review discusses the progress and challenges in delivering CRISPR/Cas9 systems for in vivo genome editing, highlighting current methods and opportunities for future therapeutic applications.

This review explores how sex differences influence the pathophysiology, incidence, and treatment outcomes of ischaemic heart disease, and emphasizes the need for more sex-specific research.

This review discusses the progress in tooth regeneration research and highlights the potential of spatial-temporal release of developmental factors, but it reports no new clinical findings.

This study found that topical application of Morinda pubescens fruit extract significantly accelerated wound healing and hair regrowth in rats compared to controls, with complete wound contraction and new hair growth observed in treated animals.

In this study, extracts from three Polynesian plants—Bidens pilosa, Calophyllum inophyllum, and Fagraea berteroana—were found to increase dermal papilla cell proliferation and modulate hair growth-related gene expression, suggesting potential for stimulating hair growth.

In this study, researchers highlighted the high global prevalence of immune-related skin diseases like dermatitis and psoriasis, noting that females are disproportionately affected, emphasizing the need for tailored public health strategies based on sex and region.

This review discusses the potential impact of COVID-19 on the male reproductive system and highlights unanswered questions regarding its mechanisms and implications for men's health and fertility, reporting no new clinical results.

This review discusses recent advances in stimuli-responsive nanoformulations for CRISPR-Cas9 delivery, highlighting their design rationales and potential biomedical applications, but reports no new experimental results.

In this literature review, researchers identified 68 African plants used in hair treatment, noting that 58 of these may also help with glucose metabolism issues, suggesting a nutritional therapy approach might explain their benefits.

This review highlights how nanotechnology enhances CRISPR-Cas9's potential for cancer treatment by improving delivery and stability, addressing key challenges like immunogenicity and delivery inefficiencies, and discusses recent advancements in stimuli-responsive nanoplatforms for precise genome editing.

This study investigated the production of β-cyclodextrin from ginkgo seeds, finding that a pretreatment scheme involving high-temperature gelatinization significantly improved the conversion rate to 72.63%, highlighting the industrial potential of underutilized ginkgo seed powder for sustainable applications.

This case study of a 45-year-old man from Tonga describes the identification of pachyonychia congenita through genetic testing, revealing a mutation in the keratin gene KRT16, associated with chronic painful skin and nail conditions.

In this study, mozuku-derived ultra-high-molecular-weight fucoidan was found to inhibit the growth of skin bacteria like Staphylococcus aureus but not other tested bacteria such as Cutibacterium acnes.

In this six-year study of a Saudi cohort, oral tofacitinib showed favorable long-term effectiveness for patients with AA, with manageable adverse events requiring regular monitoring.

This study examined the formulation of an oil derived from Alkanna tinctoria roots, traditionally used for hair health, and discusses its potential benefits for controlling hair loss, baldness, and premature greying, while promoting hair growth.

This study assessed oral tofacitinib's effectiveness and safety in treating different forms of alopecia, finding that 80% of patients experienced hair regrowth improvements over 24 weeks with no adverse events reported.

This study found that prolonged tofacitinib treatment in adult Indian patients with moderate-to-severe alopecia areata was associated with a high regrowth rate, which varied with factors like age at disease onset and treatment duration.

This observational study provides cause-specific mortality estimates to help patients and physicians better understand long-term outcomes for localized prostate cancer based on initial treatment choices.

This study found that finasteride was nongenotoxic in Drosophila, while doxazosin mesylate and saw palmetto induced homologous recombination, indicating potential genotoxic actions under the test conditions.

This study found that treating rice seeds with essential oil and Tithonia diversifolia powder increased yield and adaptation in NERICA varieties under rainy upland conditions, suggesting these treatments may improve rice production.

In this study, the researchers described a formulation process for Ratanjot hair oil using Alkanna tinctoria roots, reporting traditional uses of the oil in preventing hair loss, baldness, premature greying, and promoting hair growth, but did not present empirical results.

In this quasi-experimental study, 24-week tofacitinib treatment significantly improved hair regrowth in South Asian patients with alopecia areata, but a high relapse rate post-withdrawal signals the need for continuous treatment strategies.

Temporal triangular alopecia is a non-scarring hair loss seen in some Asian children.

This article describes the use of Croton tiglum seeds and Zingiber officianalis extract in treating alopecia areata with significant results, but does not report new clinical findings.