Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review discusses the roles of key developmental signaling pathways in mammalian skin repair compared to skin development, and suggests these insights could lead to better wound healing therapies, but it reports no new findings.

This paper discusses the role of steroid sulfatase in hormone-dependent tumors and highlights the development of potent inhibitors, noting the commencement of a phase I trial for one inhibitor in postmenopausal breast cancer patients.

This article reviews the potential clinical use of anabolic steroids in treating muscle loss from chronic diseases and aging and highlights both the benefits and risks of these substances in sports.

This review focuses on coumarin analogs with potential antibreast cancer activities but reports no new clinical results, highlighting their mechanisms of action and structure-activity relationships.

This review discusses recent advances in surface modification and endothelialization of biomaterials for vascular grafts, highlighting promising methods like gene engineering and targeting ligand immobilization to improve clinical outcomes.

This study found that corporate social responsibility can enhance consumer perceptions of product performance, especially when viewed as motivated by genuine benevolence rather than self-interest.

This review discusses the relationship between polycystic ovary syndrome and cardiovascular risk, noting a possible adverse impact on risk profiles and subclinical atherosclerosis but no clear increase in premenopausal cardiovascular events; it presents no new clinical results.

This study developed molecular signatures for dermal papilla cells and their niche, uncovering novel signaling regulators and genes linked to hair disorders, which may inform future hair development research.

This study estimates the total cost of evaluating and treating polycystic ovary syndrome in reproductive-aged women in the United States to be $4.36 billion, suggesting more liberal screening could be beneficial.

This review explores various theories of colorectal cancer stem cell biology and highlights the need for better identification and targeting of these cells to advance treatment strategies, but reports no new clinical findings.

This study suggests that phenotypic plasticity, including processes like dedifferentiation and transdifferentiation, plays a crucial role in cancer initiation, progression, and therapy resistance, broadening our understanding of cancer dynamics and potential treatment strategies.

This review discusses the role of DHEA in intracrinology, highlighting its impact on breast and prostate cancer treatment and potential as a menopause therapy, but reports no new research findings.

This review discusses the biology and development of skin melanocytes, but reports no new clinical findings.

This review discusses the neurobiology of sexual function and reports no new results; the authors cover multiple endocrine and neurotransmitter influences on sexual desire, arousal, and orgasm stages.

This document extends previous recommendations by the National Lipid Association for managing dyslipidemia, focusing on lifestyle therapies, special patient groups, and strategies to enhance adherence and patient outcomes.

This review concluded that corticosteroids improve muscle strength and function in boys with Duchenne muscular dystrophy over short-term periods, but evidence on prolonging walking ability remains insufficient, and side effects are common.

This review discusses the epidemiology, causes, diagnosis, and management of hirsutism in women, noting that effective treatment requires addressing the root cause as well as the hair growth.

This review discusses the brain-skin connection, the skin's role in stress response, and highlights unmet challenges in understanding stress-induced skin inflammation but reports no new experimental findings.

This article reviews the stages and regulation of the hair cycle, highlighting molecular regulators involved, but it does not present new research findings.

This review examines the best available evidence for diagnosing and managing PCOS but reports no new clinical results.

This review discusses the potential benefits of myo-inositol supplementation for insulin resistance-related disorders and diabetic complications, but reports no new clinical results.

This study found that specific human hair keratins are differentially expressed in the hair follicle, suggesting a shared pathway of epithelial differentiation between hair cortex and nail plate cells.

This study found that abolishing H3K27me3 in mouse skin by targeting Ezh2 and Ezh1 affects hair follicle development and epidermal behavior, revealing functional differences between these tissues.

This review discusses the use of platelet-rich plasma in dermatology for various applications such as tissue regeneration and wound healing, but it reports no new clinical results and calls for clearer guidance on suitable treatments.

This review discusses the various evidence-based and potential applications of metformin in treating and preventing symptoms and complications associated with polycystic ovary syndrome but reports no new clinical results.

This article reviews the multifunctional roles of calreticulin outside the ER and highlights its impact on wound healing in animal models, but reports no new clinical results.

This article reviews the design and objectives of the Rotterdam Study, as well as summarizes major findings, without reporting new results.

This study reports that progressive frontal fibrosing alopecia, a distinct and gradually stabilizing form of lichen planopilaris affecting elderly women and often involving eyebrow hair loss, lacks effective treatments.

This review discusses the role of Lgr5 as a marker for identifying adult stem cells, particularly in the intestine and hair follicles, and reports no clinical results.

This study found that super-enhancers are essential for hair follicle stem cell identity, lineage commitment, and plasticity in mice, with SOX9 being a key regulator of these chromatin dynamics.