This chapter explores the potential of phytochemicals in modulating human endocrine function, emphasizing the growing interest in plant-derived alternatives to synthetic medications for managing metabolic and hormonal disorders often linked to chemical exposures and lifestyle factors.
November 2014 in “Prescriber” This article presents a case history of hair loss in a 16-year-old girl and provides no new research findings.
2 citations
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June 2020 in “AIDS” This case study describes a severe instance of iatrogenic Cushing's syndrome induced by gamma-hydroxybutyric acid, exacerbated by combined use of betamethasone and anabolic steroids, in an HIV-positive patient on cobicistat-containing therapy.
October 2015 in “Elsevier eBooks” Aldesleukin can treat certain cancers and increase HIV patient CD4+ counts but often causes severe side effects.
November 2025 in “Scientific Reports” This study found that metabolic dysfunction-associated steatotic liver disease is linked to a higher risk of androgenetic alopecia, especially in women and individuals with certain lifestyle patterns.
28 citations
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January 2013 in “Journal of Thyroid Research” This review discusses the potential therapeutic use of thyroid hormones on skin conditions, highlighting the need for further research but reporting no new experimental results.
22 citations
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June 2005 in “Clinical Oncology” This case report documents an instance of symptomatic hypothyroidism developing in a patient with papillary thyroid carcinoma after beginning treatment with orlistat.
11 citations
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October 2011 in “Dermato-endocrinology” This study revealed that manual thyroid examinations in alopecia patients may uncover thyroid abnormalities undetectable by blood tests alone, but further research is needed to assess their clinical importance.
4 citations
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November 2016 in “Archives of Endocrinology and Metabolism” This study found that thyroid volume was increased in PCOS patients with insulin resistance, with potential influences from TSH and LH levels on these changes.
April 2025 in “International Journal of Research in Dermatology” This study investigated cutaneous manifestations in thyroid disorder patients, finding that hypothyroid patients commonly experienced dry skin (67.83%) while warm skin (93.3%) and increased sweating prevailed in hyperthyroid patients, with urticaria being the most common autoimmune association among both groups.
January 2024 in “International Journal of Medicine in Developing Countries” This study in Alahsa, Saudi Arabia, found that the majority of the general population has limited awareness of thyroid disease symptoms and risk factors, with only 21.8% demonstrating good knowledge about the disorders.
February 2021 in “PARIPEX INDIAN JOURNAL OF RESEARCH” This study found that women with PCOS had a higher prevalence of hypothyroidism compared to those without PCOS, especially among the obese PCOS subgroup.
24 citations
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June 2018 in “Reviews in endocrine and metabolic disorders” This review discusses the epidemiology, clinical manifestations, and pathogenesis of autoimmune skin diseases and their associations with thyroid diseases, reporting no new clinical results.
January 2023 in “European endocrinology” This review explores the association between alopecia and thyroid autoimmune disease, also highlighting a linked increased risk of thyroid cancer, but presents no new clinical findings.
176 citations
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June 2017 in “Sexual Medicine Reviews” This review discusses the increasing prevalence of erectile dysfunction in young men and emphasizes the importance of identifying specific causes for effective management, reporting no new clinical results.
3 citations
,
June 2025 in “Drug Design Development and Therapy” This review highlights the role of disrupted glycolysis in exacerbating reproductive and metabolic abnormalities in PCOS and suggests that agents like metformin and resveratrol may help restore glycolytic balance and improve ovarian function.
1 citations
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July 2015 in “Cambridge University Press eBooks” Testosterone therapy can improve sexual function in women but long-term safety is unclear.
115 citations
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August 2008 in “The Journal of Clinical Endocrinology & Metabolism” In this study, T3 and T4 were found to directly influence human hair follicles in vitro, enhancing keratinocyte proliferation, prolonging the hair growth phase, and affecting pigmentation.
107 citations
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August 2002 in “Journal of Neurology, Neurosurgery, and Psychiatry” Women with epilepsy should be monitored for reproductive issues, which can be caused by epilepsy or its treatments, especially when using valproate.
34 citations
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January 2008 in “International Review of Neurobiology” This review discusses the interplay between epilepsy and reproductive endocrine disorders, examining the factors involved and emphasizing the importance of monitoring but reports no new research findings.
12 citations
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February 2010 in “Journal of the European Academy of Dermatology and Venereology” Some people with chronic hair loss may have thyroid autoimmunity.
7 citations
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October 2020 in “Wiener medizinische Wochenschrift” This paper presents a case study of a 21-year-old male with thyroid hemiagenesis, where the left thyroid lobe and isthmus are absent, and discusses the anomaly's potential clinical consequences based on existing literature.
6 citations
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January 2007 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” This study found that topical application of triiodothyronine (T3) can induce the transition of hair follicles from the telogen to the anagen phase in mice and stimulate hair shaft growth in vitro.
2 citations
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July 2012 in “InTech eBooks” This article reviews the influence of thyroid hormone on skin and hair health, emphasizing its role in epidermal homeostasis and hair growth, but reports no new experimental results.
January 2026 in “International Journal of Homoeopathic Sciences” In this case study, a 26-year-old woman with hypothyroidism experienced significant improvements in energy, emotional balance, and physical discomfort after individualized homeopathic treatment with Kalium carbonium, demonstrating the potential benefits of a holistic approach to care.
November 2025 in “International Journal of Pharmaceutical Sciences and Drug Research” In this study, thyroid disorders were found to significantly affect physical and emotional well-being, with notable prevalence in married, urban, and non-working participants in South India.
September 2025 in “Online Türk Sağlık Bilimleri Dergisi” This study observed that pediatric patients with diffuse, non-scarring alopecia had significantly lower levels of zinc and folate compared to matched healthy controls, suggesting a possible link between these deficiencies and hair loss in children.
February 2025 in “Revista Eletrônica Acervo Saúde” This report emphasizes the importance of considering thyroid tuberculosis in the differential diagnosis of cervical masses, highlighting the role of biopsy and histopathological examination for accurate diagnosis and treatment.
November 2024 in “Malaysian Journal of Microbiology” In this study, researchers found varying levels of multiple autoantibody types among thyroid disorder patients, with 84.84% of those with immunological hypothyroidism reporting symptoms like weight gain and lethargy, whereas 81.81% of those with immune hyperthyroidism experienced hair loss.
This study observed that individuals with autoimmune thyroid disease in Georgia had significantly higher frequencies of certain symptoms and Anti-TPO levels compared to controls, with no significant difference in vitamin D levels.