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Testosterone helps prevent skin damage in males by acting through both estrogen and androgen pathways.

Treatments that reduce oxidative stress and fix mitochondrial problems may help heal chronic wounds.

Rivaroxaban can cause liver injury, allergic reactions, blood vessel inflammation, and hair loss, but these side effects are rare.

Hair loss linked to heart disease in young men.

Metformin and rosiglitazone improve blood vessel function in women with PCOS, with metformin also reducing insulin resistance and testosterone levels.

Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.

Skin aging reflects overall body aging and can indicate internal health conditions.

Polycystic ovary syndrome costs the U.S. over $4 billion a year, mainly from treating related health issues.

Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.

The conclusion is that off-label drug use can lead to important medical discoveries and improve patient care.

Hidden fungal infections might cause heart disease and clogged arteries.

Long-term estrogen therapy in postmenopausal women can improve certain health markers, hair loss is common regardless of hormone use, stopping estrogen doesn't increase breast cancer risk, smoking does, and a balanced BMI is linked to lower mortality.

Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.

UVB is good for a skin condition in Asian kids, a lotion works for head lice, a drug helps with a skin blistering disorder, a foam reduces itchiness in skin inflammation, birthmarks can be more widespread, and criteria for a neurocutaneous disorder were agreed upon.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Photobiomodulation therapy using red and near-infrared light can reduce inflammation and aid in healing various conditions.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

The conclusion is that using drugs to block the TOR pathway might slow aging and prevent age-related diseases.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Insulin resistance may contribute to various skin diseases and treating it could improve skin health and prevent more serious conditions.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.

Drug repurposing is a cost-effective way to find new uses for existing drugs, speeding up treatment development.

Testosterone therapy is beneficial for women's health and does not cause masculinization or liver damage, and it protects the heart and breasts.

Cyproterone acetate treatment is safe and causes mild feminization, which increases with added estrogen.

Chlormadinone acetate is a strong, well-tolerated hormone used in birth control and hormone therapy with benefits for menstrual pain and skin conditions.

For women with moderate to severe unwanted hair growth or acne, birth control pills are the first choice, with other medications like cyproterone, spironolactone, flutamide, or finasteride as alternatives, and permanent hair removal should be done with electrolysis or laser.