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The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Dermoscopy is a useful tool for identifying features of skin conditions, but more research is needed to define its role in dermatology.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Nerves are crucial for the regeneration of various body parts in many animals.

Cells from balding scalps have more androgen receptors than cells from non-balding scalps.

Testing basal 17-HP levels is a good way to screen for nonclassic adrenal hyperplasia in women with high androgen levels.

Noggin is necessary to start the hair growth phase in skin after birth.

Androgens can both increase and decrease hair growth in different parts of the body.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

Androgens may cause hair loss by increasing TGF-beta1 from scalp cells, which inhibits hair cell growth.

Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Biotinidase deficiency has various symptoms and can be treated with biotin supplements.

Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Hair follicles significantly increase the speed and amount of caffeine absorbed through the skin.

Hair loss in men is common, treatable, but not curable.

Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Latanoprost can make eyelashes longer, thicker, and darker.

Certain inhibitors slow down plant growth by causing early cell specialization without changing the cell development pattern.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Male pattern baldness involves genetics, hormones, and needs better treatments.