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The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Dermatoscopy is useful for identifying different hair and scalp conditions and can reduce the need for biopsies.

Dermoscopy is a useful tool for identifying features of skin conditions, but more research is needed to define its role in dermatology.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

The report recommends personalized treatment for women's sexual dysfunctions and more research on effective therapies.

Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.

Middle-aged women with chronic telogen effluvium experience increased hair shedding but usually don't get significantly thinner hair.

Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

The document provides a method to classify human hair growth stages using a model with human scalp on mice, aiming to standardize hair research.

More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.

The skin is a complex barrier for drug penetration, but understanding its structure and interactions can improve drug delivery methods.

Androgens can both increase and decrease hair growth in different parts of the body.

PGD2 stops hair growth and is higher in bald men with AGA.

Lactate production is important for activating hair growth stem cells.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

The cuneate nucleus has two main neuron types: relay neurons and interneurons.

Visible light can damage skin and most sunscreens don't block it well; more research is needed on its effects and protection methods.

Fungi-produced compounds can change plant root growth.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Targeted cancer therapies often cause serious skin problems that need careful management.

Hair and wool have complex microscopic structures with microfibrils and varying cystine content.

Sulforaphane from broccoli can help protect skin from sun damage.

Special fiber materials boost the healing properties of certain stem cells.

Hair follicles significantly increase the speed and amount of caffeine absorbed through the skin.

Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.

Cancer treatments targeting specific cells and the immune system can cause skin, mouth, hair, and nail problems, affecting patients' quality of life and treatment adherence.

Regenerated fully functional hair follicles using stem cells, with potential for hair regrowth therapy.