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    Did you mean TGF-beta signaling?
    Glossary TGF-beta signaling

    cellular communication process regulating growth, differentiation, and immune responses

    TGF-beta signaling, or Transforming Growth Factor-beta signaling, is a cellular communication process that regulates various biological functions, including cell growth, differentiation, and immune responses. This pathway involves the binding of TGF-beta proteins to specific receptors on the cell surface, which then activate intracellular molecules called SMADs to transmit signals to the nucleus, influencing gene expression. This pathway is crucial in maintaining tissue homeostasis and has implications in conditions like cancer, fibrosis, and alopecia.

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    1. Exploring the Complexities of TGF-beta Signaling in Keloids: Beyond the Classical Smad Pathway International Journal of Molecular Sciences · 2026
    2. Injectable platelet-rich fibrin promotes proliferation and trichogenic inductivityof dermal papilla cells through activating TGF-β/Smad signaling pathway Cellular and Molecular Biology · 2024 · 4 citations
    3. From hair to liver: emerging application of hair follicle mesenchymal stem cell transplantation reverses liver cirrhosis by blocking the TGF-β/Smad signaling pathway to inhibit pathological HSC activation PeerJ · 2022 · 4 citations
    4. Cooperation of TGF‐β and FGF signalling pathways in skin development Cell Proliferation · 2023 · 23 citations
    5. Hair Follicle Development of Rex Rabbits Is Regulated Seasonally by Wnt10b/β-Catenin, TGFβ-BMP, IGF1, and EGF Signaling Pathways Animals · 2023 · 1 citations
    6. Network pharmacology and in vivo experimental analysis for validating the antifibrotic potential of Punica granatum leaves against skin scleroderma: the role of oxidative stress, inflammation and TGF-β1/Snail 1/p-Smad 3 signaling pathway Inflammopharmacology · 2026
    7. TGFβ signaling regulates lipogenesis in human sebaceous glands cells BMC Dermatology · 2013 · 44 citations
    8. CXXC5: A novel regulator and coordinator of TGF-β, BMP and Wnt signaling Journal of Cellular and Molecular Medicine · 2018 · 28 citations
    9. Co-opting Developmental Signaling Pathways to Promote Wound Healing Recent clinical techniques, results, and research in wounds · 2018 · 1 citations
    10. TGF-β Family Signaling in Epithelial Differentiation and Epithelial–Mesenchymal Transition Cold Spring Harbor Perspectives in Biology · 2017 · 82 citations
    11. Identification of key genes and signaling pathways related to Hetian sheep wool density by RNA-seq technology PLOS ONE · 2022 · 7 citations
    12. Hair-Growth-Promoting Effects of the Fish Collagen Peptide in Human Dermal Papilla Cells and C57BL/6 Mice Modulating Wnt/β-Catenin and BMP Signaling Pathways International Journal of Molecular Sciences · 2022
    13. Ginsenoside CK inhibits androgenetic alopecia by regulating Wnt/β‐catenin and p53 signaling pathways in AGA mice Food frontiers · 2023
    14. Edar Signaling in the Control of Hair Follicle Development 2005 · 71 citations
    15. MiR-23b and miR-133 cotarget TGFβ2/NOTCH1 in dermal fibroblasts and affect hair follicle development in sheep Research Square (Research Square) · 2023
    16. Let-7b promotes alpaca hair growth via transcriptional repression of TGFβR I Gene · 2015 · 13 citations
    17. 484 Transforming growth factor-β signaling-mediated wound healing is required hair follicle neogenesis Journal of Investigative Dermatology · 2024
    18. Hedgehog signaling reprograms hair follicle niche fibroblasts to a hyper-activated state Developmental cell · 2022 · 25 citations
    19. TGFβ family mimetic peptide promotes proliferation of human hair follicle dermal papilla cells and hair growth in C57BL/6 mice Biomedical dermatology · 2018 · 9 citations
    20. LB1671 Large-scale skin scRNA-seq profiling highlights distinct body site-specific ligand-receptor interactions and pathways in keratinocytes Journal of Investigative Dermatology · 2023
    21. Regulatory pathways implicated in male androgenetic alopecia pathogenesis British Journal of Dermatology · 2017
    22. LncRNA PlncRNA‑1 regulates proliferation and differentiation of hair follicle stem cells through TGF‑β1‑mediated Wnt/β‑catenin signal pathway Molecular Medicine Reports · 2017 · 25 citations
    23. Dermal Blimp1 Acts Downstream of Epidermal TGFβ and Wnt/β-Catenin to Regulate Hair Follicle Formation and Growth Journal of Investigative Dermatology · 2017 · 85 citations
    24. The Harmonies Played by TGF-β in Stem Cell Biology Cell Stem Cell · 2012 · 156 citations
    25. All-trans retinoic acid modulates proliferation and apoptosis of secondary hair follicle–dermal papilla cells in cashmere goats via the TGF-β2/Smad2/3 pathway Frontiers in Veterinary Science · 2026
    26. 1407 Mechanical force activation of TGF-β signaling controls hair follicle regression Journal of Investigative Dermatology · 2023
    27. Large Scale Gene Expression Profiles of Regenerating Inner Ear Sensory Epithelia PLoS ONE · 2007 · 77 citations
    28. Wound healing in development Birth Defects Research · 2012 · 29 citations
    29. Expression Profiling Reveals Genes Involved in the Regulation of Wool Follicle Bulb Regression and Regeneration in Sheep International Journal of Molecular Sciences · 2015 · 19 citations
    30. MSC-EVs and UCB-EVs promote skin wound healing and spatial transcriptome analysis Scientific Reports · 2025 · 12 citations