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    Did you mean TGF-beta signaling?
    Glossary TGF-beta signaling

    cellular communication process regulating growth, differentiation, and immune responses

    TGF-beta signaling, or Transforming Growth Factor-beta signaling, is a cellular communication process that regulates various biological functions, including cell growth, differentiation, and immune responses. This pathway involves the binding of TGF-beta proteins to specific receptors on the cell surface, which then activate intracellular molecules called SMADs to transmit signals to the nucleus, influencing gene expression. This pathway is crucial in maintaining tissue homeostasis and has implications in conditions like cancer, fibrosis, and alopecia.

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    1. Paracrine TGF-β Signaling Counterbalances BMP-Mediated Repression in Hair Follicle Stem Cell Activation Cell stem cell · 2012 · 321 citations
    2. CXXC5: A novel regulator and coordinator of TGF-β, BMP and Wnt signaling Journal of Cellular and Molecular Medicine · 2018 · 28 citations
    3. Hair Follicle Development of Rex Rabbits Is Regulated Seasonally by Wnt10b/β-Catenin, TGFβ-BMP, IGF1, and EGF Signaling Pathways Animals · 2023 · 1 citations
    4. TGF-β Family Signaling in Epithelial Differentiation and Epithelial–Mesenchymal Transition Cold Spring Harbor Perspectives in Biology · 2017 · 82 citations
    5. A role for the Tgf-β/Bmp co-receptor Endoglin in the molecular oscillator that regulates the hair follicle cycle Journal of Molecular Cell Biology · 2018 · 26 citations
    6. Hair-Growth-Promoting Effects of the Fish Collagen Peptide in Human Dermal Papilla Cells and C57BL/6 Mice Modulating Wnt/β-Catenin and BMP Signaling Pathways International Journal of Molecular Sciences · 2022
    7. A role for the Tgf-β/Bmp co-receptor Endoglin in the molecular oscillator that regulates the hair follicle cycle bioRxiv (Cold Spring Harbor Laboratory) · 2017
    8. Hair Follicle Stem Cells: the Signaling Hub of the Skin Journal of cellular immunology · 2024
    9. Edar Signaling in the Control of Hair Follicle Development 2005 · 71 citations
    10. Dermal niche signaling and epidermal stem cells Advances in stem cells and their niches · 2019
    11. Identification of key genes and signaling pathways related to Hetian sheep wool density by RNA-seq technology PLOS ONE · 2022 · 7 citations
    12. Comparative Transcriptome Analysis of Fetal Skin Reveals Key Genes Related to Hair Follicle Morphogenesis in Cashmere Goats PLoS ONE · 2016 · 127 citations
    13. The Role of Smads in Skin Development 2008 · 59 citations
    14. Data from Elevated Cutaneous Smad Activation Associates with Enhanced Skin Tumor Susceptibility in Organ Transplant Recipients 2023
    15. Expression Profiling Reveals Genes Involved in the Regulation of Wool Follicle Bulb Regression and Regeneration in Sheep International Journal of Molecular Sciences · 2015 · 19 citations
    16. Effects of TGFBR1 on Proliferation of Dermal Papilla Cells in Fine-Wool Sheep Animals · 2025
    17. Defining the Localization and Molecular Characteristic of Minor Salivary Gland Label-Retaining Cells Stem cells · 2014 · 18 citations
    18. Defining and targeting differentiation of non-melanoma skin cancer 2014
    19. Regulatory pathways implicated in male androgenetic alopecia pathogenesis British Journal of Dermatology · 2017
    20. iTRAQ-Based Quantitative Proteomic Comparison of Early- and Late-Passage Human Dermal Papilla Cell Secretome in Relation to Inducing Hair Follicle Regeneration PLOS ONE · 2016 · 19 citations
    21. Gene Expression Profiling of the Intact Dermal Sheath Cup of Human Hair Follicles Acta dermato-venereologica · 2018 · 11 citations
    22. Cooperation of TGF‐β and FGF signalling pathways in skin development Cell Proliferation · 2023 · 23 citations
    23. New Activators and Inhibitors in the Hair Cycle Clock: Targeting Stem Cells’ State of Competence Journal of Investigative Dermatology · 2012 · 68 citations
    24. Neural Stem Cells Restore Hair Growth through Activation of the Hair Follicle Niche Cell Transplantation · 2016 · 14 citations
    25. Mesenchymal–epithelial interactions during hair follicle morphogenesis and cycling Seminars in Cell & Developmental Biology · 2012 · 300 citations
    26. Fibroblasts: Origins, definitions, and functions in health and disease Cell · 2021 · 488 citations
    27. In Vitro Hair Dermal Papilla Cells Induction by Fagraea berteroana, a Tree of the Marquesan Cosmetopoeia (French Polynesia) Cosmetics · 2021 · 1 citations
    28. Recent advances in exosomal non‐coding RNA‐based therapeutic approaches for photoaging Skin research and technology · 2023 · 3 citations
    29. High-Throughput Sequencing Reveals miRNAs Affecting Follicle Development in Chicken International journal of genetics and genomics · 2017 · 2 citations
    30. Can Plant Extracts Help Prevent Hair Loss or Promote Hair Growth? A Review Comparing Their Therapeutic Efficacies, Phytochemical Components, and Modulatory Targets 2024