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The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Thymus transplantation successfully restored immune function in infants with FOXN1 deficiency.

The document concludes that diagnosing and treating Human African Trypanosomiasis is challenging, but new treatments like fexinidazole are promising.

Early diagnosis and treatment are crucial for preventing permanent hair loss in various scalp conditions, and while new treatments are promising, more research is needed to evaluate their effectiveness.

Old treatments for other skin conditions showed promise for hair regrowth in mice with a hair loss condition.

Teriflunomide is an effective and safe first-line oral treatment for relapsing multiple sclerosis.

Some treatments can stabilize Frontal Fibrosing Alopecia, but more research is needed to find effective treatments, and hair transplants often fail.

Treat limited stage small cell lung cancer with chemotherapy and radiation, and consider preventive brain radiation for better survival chances.

Some treatments can help hair regrowth in alopecia areata, but none offer a cure, and effectiveness varies.

The trial showed that a new under-the-tongue treatment for severe hair loss was somewhat effective in a small group of people.

Minoxidil works faster, but ketoconazole is a safer alternative for female hair loss.

Diphenylcyclopropenone is effective for treating alopecia areata but has a high relapse rate.

Leflunomide and methotrexate are similarly effective for rheumatoid arthritis but have different side effects.

In June 2019, the stem cell research field saw major progress, including new clinical trials, FDA approvals, and industry collaborations.

Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.

Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

There are many treatments for permanent hair loss disorders, but their effectiveness varies and there's no clear best option.

Epidermal stem cells could lead to new treatments for skin and hair disorders.

Apoptosis is crucial for healthy skin and treating skin diseases.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.

The length of the CAG repeat in the androgen receptor gene affects the risk and progression of prostate cancer, BPH, infertility, and undermasculinized genitalia.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.

Leflunomide and methotrexate are equally effective for rheumatoid arthritis but have different side effects.

Toxic shock syndrome is caused by a complex interaction of bacterial toxins and the immune system, and understanding this can help improve diagnosis and treatment.

No treatments fully cure or prevent alopecia areata; some help but have side effects or need more research.