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    Did you mean T-helper 2 cell?
    Glossary T-helper 2 cell

    immune cell involved in allergic reactions and parasite defense

    A T-helper 2 (Th2) cell is a type of immune cell that plays a crucial role in the body's defense against extracellular parasites, such as helminths, and is also involved in allergic reactions. Th2 cells produce cytokines like IL-4, IL-5, and IL-13, which help stimulate the production of antibodies by B cells and promote the activation of other immune cells.

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    1. T helper 17 cell/regulatory T-cell imbalance in hidradenitis suppurativa/acne inversa: the link to hair follicle dissection, obesity, smoking and autoimmune comorbidities 2018 · 66 citations
    2. Imbalance of T‐helper 17 and regulatory T cells in patients with alopecia areata The Journal of Dermatology · 2015 · 62 citations
    3. 42905 Role of regulatory T and T-helper 17 cells in patients with acute diffuse and total alopecia Journal of the American Academy of Dermatology · 2023
    4. MicroRNA-1246 Inhibits NFATc1 Phosphorylation and Regulates T Helper 17 Cell Activation in the Pathogenesis of Severe Alopecia Areata 2023
    5. The Role of T‐Helper 17 Cells and Regulatory T Cells in Acute Diffuse and Total Alopecia: The Increased Function of Regulatory T Cells May Explain the Favorable Prognosis The Journal of Dermatology · 2025 · 1 citations
    6. Detection of subtypes of T helper cells and their cytokines in peripheral blood of patients with systematic lupus erythematosus and their clinical significances Journal of Jilin University · 2014
    7. The Phenotype of Circulating Follicular-Helper T Cells in Patients with Rheumatoid Arthritis Defines CD200 as a Potential Therapeutic Target Clinical & Developmental Immunology · 2012 · 32 citations
    8. The potential of regulatory T cell-based therapies for alopecia areata Frontiers in Immunology · 2023
    9. Role of regulatory T cells in psoriasis pathogenesis and treatment British Journal of Dermatology · 2020 · 273 citations
    10. Frontal fibrosing alopecia shows robust T helper 1 and Janus kinase 3 skewing 2020 · 34 citations
    11. CD4 T cells from mice with alopecia areata express an effector like phenotype and can transfer disease The Journal of Immunology · 2023 · 1 citations
    12. T Cells Promote Distinct Transcriptional Programs of Cutaneous Inflammatory Disease in Keratinocytes and Dermal Fibroblasts Journal of Investigative Dermatology · 2025 · 2 citations
    13. P130 The densities of T cells, Langerhans cells, and natural killer cells in uninvolved skin of patients with acne vulgaris Journal of the European Academy of Dermatology and Venereology · 1997
    14. 290 Brepocitinib improves cicatricial alopecia and downregulates key T-helper biomarkers Journal of Investigative Dermatology · 2024
    15. Class IIa HDAC4 and HDAC7 cooperatively regulate gene transcription in Th17 cell differentiation Proceedings of the National Academy of Sciences · 2024 · 16 citations
    16. The role of natural killer cells in autoimmune blistering diseases Autoimmunity · 2011 · 24 citations
    17. Sphingolipid metabolism orchestrates the establishment of the adult hair follicle stem cell niche to control skin homeostasis bioRxiv (Cold Spring Harbor Laboratory) · 2024
    18. 176 Myeloid cell-specific deletion of mTOR suppresses psoriasis-like skin inflammation in C57BL/6 mice Journal of Investigative Dermatology · 2023
    19. Decision letter: Role of distinct fibroblast lineages and immune cells in dermal repair following UV radiation-induced tissue damage 2021
    20. PD-1+CXCR5−CD4+T cells are correlated with the severity of systemic lupus erythematosus Rheumatology · 2019 · 71 citations
    21. A humanized IL-2 fusion protein enhances T regulatory cells in vivo and restrains disease in a murine model of Alopecia Areata 4760 The Journal of Immunology · 2025
    22. Postmenopausal frontal fibrosing alopecia. Scarring alopecia in a pattern distribution Archives of Dermatology · 1994 · 332 citations
    23. Postmenopausal Frontal Fibrosing Alopecia Archives of Dermatology · 1994 · 325 citations
    24. Targeting lymphoid-derived IL-17 signaling to delay skin aging Nature Aging · 2023 · 59 citations
    25. Sebaceous Gland, Hair Shaft, and Epidermal Barrier Abnormalities in Keratosis Pilaris with and without Filaggrin Deficiency ˜The œAmerican journal of pathology · 2015 · 23 citations
    26. Androgenetic alopecia and hair growth promotion state of the art: Present and future Clinics in Dermatology · 1988 · 8 citations
    27. Lupus comédonien Annales de Dermatologie et de Vénéréologie · 2007 · 7 citations
    28. Alopecia Areata: A Complex Cytokine Driven Disease 2020 · 3 citations
    29. Alopecia areata and risk of atopic and autoimmune conditions: population-based cohort study Clinical and Experimental Dermatology · 2022 · 34 citations
    30. An ROS‐Scavenging Treg‐Recruiting Hydrogel Patch for Diabetic Wound Healing Advanced Functional Materials · 2024