September 2018 in “Practical diabetes” This article reviews various skin conditions and infections associated with diabetes, noting that people with diabetes are at higher risk for skin conditions such as cellulitis, folliculitis, and skin cancer, and reports no new clinical results.
April 2019 in “Journal of the Endocrine Society” This study found that in male mouse pancreatic islet β cells, testosterone enhances glucose-stimulated insulin secretion by being locally converted into dihydrotestosterone and estradiol.
This chapter reviews the pathophysiology of immune checkpoint inhibitor-related endocrinopathies and examines the rationale for using advanced diabetes care technologies, like pump therapies and continuous glucose monitors, in managing these conditions.
2 citations
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December 2024 in “eLife” This study observed that individuals with Down syndrome exhibit early immune dysregulation, including multi-organ autoimmunity and hypercytokinemia, and found that the JAK inhibitor tofacitinib showed a good safety profile and reduced skin pathology in a Phase II trial.
March 2020 in “Research Square (Research Square)” This study found that adipose-derived mesenchymal stem cells from type 2 diabetes mice are slightly less effective than controls but offer similar therapeutic benefits for wound healing.
1 citations
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January 2008 142 citations
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November 2009 in “BMC Complementary and Alternative Medicine” This study supports the traditional use of T. procumbens for diabetes treatment, showing improvements in body weight and glucose tolerance with no toxicity signs in normal rats.
In this thesis, researchers explored ways to enhance the management of myotonic dystrophy type 1 by investigating the genetic inheritance patterns, especially small-sized repeat expansions, and assessing cardiac care, energy expenditure, and body composition in affected individuals.
March 2013 in “Journal of pediatric nursing” This case report presents a 14-year-old girl with type A insulin resistance, illustrating diagnostic processes to differentiate it from type 2 diabetes in the context of pediatric obesity and hyperglycemia.
1 citations
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December 2020 in “Media Keperawatan Politeknik Kesehatan Makassar” This study describes nursing care for a patient with Type 2 Diabetes, finding that nutritional management and insulin administration improved nutritional status and controlled blood glucose levels.
1 citations
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October 2022 in “International Journal of Environmental Research and Public Health” This study found that Type 2 Diabetes was associated with a higher likelihood of Demodex folliculorum infestation in patients at a hospital in Peru.
3 citations
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August 1992 in “Bulletin of Experimental Biology and Medicine” Diabetes changes keratin in skin and hair, affecting their health.
January 2025 in “Global Health” This study found that Bangladeshi patients with type 2 diabetes mellitus had significantly lower serum vitamin E levels compared to healthy individuals, with lower levels particularly observed in female and older patients, emphasizing the potential importance of antioxidant status in managing the disease.
1 citations
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July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” In this open-label trial, Tofacitinib was well tolerated and improved IFN and cytokine scores, as well as overall skin pathology, in individuals with Down syndrome and immune skin conditions.
November 2025 in “Journal of Diabetes Investigation” In this case study, a man with Werner syndrome and diabetes saw improved glycemic control and insulin resistance with dapagliflozin, suggesting its potential usefulness for managing diabetes in similar patients.
35 citations
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February 2012 in “The New England Journal of Medicine” Early diagnosis and treatment of TPP can prevent complications.
August 2025 in “Journal of the American Academy of Dermatology” 1 citations
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August 2025 This study found that GLP-1 receptor agonists show potential for improving psoriasis and hidradenitis suppurativa by reducing inflammation and lesion severity, but they also pose dermatological risks such as alopecia and injection site reactions.
January 2026 in “Biomolecules” This review suggests that the TSC22D family genes may influence metabolism and cancer, potentially serving as a therapeutic target for conditions like diabetes, obesity, and certain tumors, depending on the tumor environment.
26 citations
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September 2023 in “Journal of Allergy and Clinical Immunology” Regulatory T cells help prevent autoimmunity and have potential for treating autoimmune diseases.
4 citations
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January 2010 in “Journal of pediatric endocrinology & metabolism/Journal of pediatric endocrinology and metabolism” This study described the clinical course of six young patients with type 1 autoimmune polyglandular failure, all of whom initially presented with hypoparathyroidism followed by mucocutaneous candidiasis and adrenal failure.
39 citations
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April 2019 in “The journal of immunology/The Journal of immunology” This study found that Malt1, particularly its protease activity, plays a crucial role in maintaining Treg cell function and homeostasis, with its inactivation leading to autoimmune diseases and altered immune responses in mice.
11 citations
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January 2020 in “Medical Journal Armed Forces India” This review discusses the various aspects of insulin resistance and highlights its potential evolutionary benefits, reporting no new experimental findings.
April 2023 in “Journal of The American Academy of Dermatology” This study investigated the association between hair loss and medications affecting the GH/IGF-1 pathway, using the FDA Adverse Event Reporting System to analyze reporting odds ratios of alopecia.
24 citations
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November 1974 in “Scottish medical journal” Diabetes often causes various skin problems and complications.
18 citations
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August 2024 in “eLife” This study investigated immune dysregulation in individuals with Down syndrome and found that treatment with the JAK inhibitor tofacitinib improved skin conditions like alopecia areata and reduced autoimmune markers without severe side effects. Additional research is necessary to understand its broader impacts.
13 citations
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April 1997 in “Biochemical and Biophysical Research Communications” This study observed that insulin-dependent diabetes induces specific molecular changes in the keratin structure of hair, potentially offering a new way to study diabetic complications through easily accessible tissues.
July 2026 in “Journal of the American Academy of Dermatology” GLP-1 and GLP-1/GIP agonists may increase the risk of hair loss.
21 citations
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May 2014 in “Toxicological Sciences” This study found that skin exposure to toluene diisocyanate in mice creates immune-recognition reservoirs in the skin's stratum corneum and hair follicles, potentially leading to sensitization and allergic reactions.
October 2022 in “The American journal of gastroenterology” This case report details a patient with myasthenia gravis and a malignant thymoma whose rising liver function tests, initially thought to be related to antibiotic use, were ultimately attributed to thymoma-associated multiorgan autoimmunity.